Streptococcus mitis str. SK642

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain SK642 is a Gram-positive, nonsporulating coccus that typically arranges itself in chains or pairs. This strain is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. As a host-associated microbe, S. mitis SK642 is often found in the human oral cavity and may play a role in the complex microbial communities that inhabit this niche. The coccoid shape and chain-pair arrangement of S. mitis SK642 are characteristic of the genus Streptococcus, which includes many species known for their diverse interactions with human hosts. The facultative anaerobic nature of this strain suggests it can adapt to varying oxygen levels, which may enhance its survivability in the dynamic environments of the oral microbiome. Understanding the traits of S. mitis SK642 contributes to our broader knowledge of oral microbiota, particularly regarding its potential interactions with other microorganisms and its role in maintaining microbial balance. This strain’s presence in host-associated habitats highlights the importance of Streptococcus species in human health, where they may influence both commensal and pathogenic dynamics within the oral ecosystem.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
StrainSK642

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis str. SK642
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain SK642 gsmSK642.contig.10_1, whole

Gene Summary

Adenine Count

592662 bp

Thymine Count

605295 bp

Guanine Count

394164 bp

Cytosine Count

397518 bp

Genome Length

1989639 bp

Protein-coding Genes

1879 genes

Non-Coding Genes

52 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nlpc/p60 family proteinSK642_0031Not AvailablePositive26586 - 2753936073.1
cell wall binding repeat family proteinSK642_0032Not AvailablePositive27651 - 2883544982.6
comc family proteinSK642_0033Not AvailablePositive28991 - 291375597.62
hypothetical proteinSK642_0034Not AvailableNegative29358 - 295346962.44
histidine kinaseSK642_0035Not AvailablePositive29585 - 3051735697.6
lyttr dna-binding domain proteinSK642_0036Not AvailablePositive30514 - 3124528610.0
class iib bacteriocin, lactobin a/cerein 7b family proteinSK642_0037Not AvailablePositive31839 - 320156459.62
hypothetical proteinSK642_0038Not AvailablePositive32247 - 324175771.83
putative membrane proteinSK642_0039Not AvailablePositive32457 - 326366988.82
putative membrane proteinSK642_0040Not AvailablePositive33332 - 335207480.91

Displaying genes 31 – 40 of 1931 in total

Metabolites

467 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000198tetracenomycin CC23H20O11Chemical structure of tetracenomycin CNot available
Average472.402Da
Monoisotopic472.100561464Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da

Displaying 1–10 of 467 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total