Streptococcus mitis str. SK578

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus mitis strain SK578 is a Gram-positive coccus that typically arranges itself in chains or pairs. This strain is nonsporulating and demonstrates facultative anaerobic respiration, allowing it to thrive in both aerobic and anaerobic environments. As a host-associated microbe, S. mitis SK578 is likely to reside within the human microbiota, particularly in the oral cavity, where it can coexist with various other microbial species. The facultative anaerobic nature of this strain suggests its adaptability to fluctuating oxygen levels, which is a common characteristic of many oral streptococci. This adaptability may play a crucial role in its survival and function within the complex oral ecosystem, where it can contribute to the maintenance of microbial balance and potentially influence host health. Given its chain and pair arrangement, S. mitis SK578 may have implications for biofilm formation, a common trait among oral streptococci. Biofilms are critical for the colonization of surfaces in the oral cavity, which can affect overall oral health and the dynamics of microbial interactions. Therefore, studying this strain can provide valuable insights into the role of Streptococcus mitis in the oral microbiome and its potential contributions to both health and disease in human hosts.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus mitis
StrainSK578

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus mitis str. SK578
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Streptococcus mitis strain SK578 gsmSK578.contig.15_1, whole

Gene Summary

Adenine Count

628893 bp

Thymine Count

620591 bp

Guanine Count

416166 bp

Cytosine Count

415141 bp

Genome Length

2080791 bp

Protein-coding Genes

1998 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
putative dna-directed rna polymerase subunit deltaSK578_0412Not AvailablePositive435223 - 43581022181.5
ctp synthaseSK578_0413Not AvailablePositive436151 - 43775859276.1
putative exported proteinSK578_0414Not AvailablePositive437850 - 43814911211.5
thioredoxin family proteinSK578_0415Not AvailablePositive438146 - 43846312231.7
putative trna binding domain proteinSK578_0416Not AvailablePositive438479 - 43910522895.6
short chain dehydrogenase family proteinSK578_0417Not AvailablePositive439147 - 43990827483.2
single-stranded dna-binding family proteinSK578_0418Not AvailablePositive439985 - 44038014853.6
10 kda chaperoninSK578_0419Not AvailablePositive440536 - 4408209911.01
chaperonin grolSK578_0420Not AvailablePositive440836 - 44245857113.8
hypothetical proteinSK578_0421Not AvailablePositive442596 - 44336329754.4

Displaying genes 451 – 460 of 2066 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Invasive streptococcal diseaseCausesPMC9328907
EndocarditisCausesPMC2828477
S. mitis meningitisCausesPMC2828477
EndocarditisCausesPMC3279804
PeritonitisCausesPMC7747055
Infective endocarditisCausesPMC3178606
Subacute infective endocarditisCausesPMC3178606

Displaying health effects 1 – 7 of 7 in total