Gardnerella vaginalis str. KA00225

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis str. KA00225 is a Gram-positive, non-sporulating rod-shaped bacterium that thrives in anaerobic conditions, with an optimal growth temperature of 37.0°C. As a chemoheterotroph, this microbe derives its energy from organic compounds, reflecting its adaptation to a host-associated habitat. The association of Gardnerella vaginalis with human hosts, particularly in the context of the female urogenital tract, underscores its potential role in the complex microbial communities present in this environment. While the specific ecological dynamics of strain KA00225 remain to be fully elucidated, its anaerobic metabolic requirements suggest a specialized niche within the predominantly anaerobic conditions of the vaginal microbiome. Research has indicated that members of the Gardnerella genus are often involved in maintaining or disrupting microbial balance in their host environments. The exclusive reliance on organic substrates for energy further emphasizes the microbe’s adaptation to nutrient-rich host-associated habitats, where it may interact with a variety of other microbial species. Understanding the metabolic and ecological roles of Gardnerella vaginalis str. KA00225 can provide insights into its contributions to the health and stability of the vaginal microbiome, as well as its potential implications for female reproductive health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
StrainKA00225

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis str. KA00225
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa, Oryctolagus cuniculus
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Gardnerella vaginalis strain KA00225 Contig_52, whole genome

Gene Summary

Adenine Count

475540 bp

Thymine Count

512835 bp

Guanine Count

368873 bp

Cytosine Count

312550 bp

Genome Length

1670019 bp

Protein-coding Genes

1181 genes

Non-Coding Genes

90 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
anchored repeat abc transporter, substrate-binding proteinBFS05_03580Not AvailablePositive868234 - 87001865513.7
anchored repeat-type abc transporter atp-binding subunitBFS05_03585Not AvailablePositive870006 - 87082730138.7
anchored repeat-type abc transporter permease subunitBFS05_03590Not AvailablePositive870827 - 87169930677.8
1-acyl-sn-glycerol-3-phosphate acyltransferaseBFS05_03595Not AvailablePositive871823 - 87271033803.0
glycerol-3-phosphate acyltransferaseBFS05_03600Not AvailablePositive872869 - 87386434194.0
d-alanine--d-alanine ligase aBFS05_03605Not AvailablePositive873934 - 87507641158.9
cpbp family intramembrane metalloprotease domain-containing proteinBFS05_03610Not AvailablePositive875230 - 87622237278.2
homoserine dehydrogenaseBFS05_03615Not AvailablePositive876436 - 87782148162.3
homoserine kinaseBFS05_03620Not AvailablePositive877841 - 87891738198.0
toxin-antitoxin system proteinBFS05_03625Not AvailablePositive879028 - 87932110962.0

Displaying genes 721 – 730 of 1271 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Pyogenic osteomyelitisCausesPMC7852921
Bacterial vaginosisCausesPMC11597594
Bacterial vaginosisCausesPMC11782042
UtisCausesPMC11782042
Bacterial vaginosisCausesPMC12054147
BvCausesPMC12519793
BvCausesPMC12800088
Bacterial vaginosisCausesPMC13228082
BvCausesPMC13228082
Bacterial vaginosisCausesPMC12281154

Displaying health effects 1 – 10 of 11 in total