Gardnerella vaginalis str. KA00225

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Gardnerella

Description

Gardnerella vaginalis str. KA00225 is a Gram-positive, non-sporulating rod-shaped bacterium that thrives in anaerobic conditions, with an optimal growth temperature of 37.0°C. As a chemoheterotroph, this microbe derives its energy from organic compounds, reflecting its adaptation to a host-associated habitat. The association of Gardnerella vaginalis with human hosts, particularly in the context of the female urogenital tract, underscores its potential role in the complex microbial communities present in this environment. While the specific ecological dynamics of strain KA00225 remain to be fully elucidated, its anaerobic metabolic requirements suggest a specialized niche within the predominantly anaerobic conditions of the vaginal microbiome. Research has indicated that members of the Gardnerella genus are often involved in maintaining or disrupting microbial balance in their host environments. The exclusive reliance on organic substrates for energy further emphasizes the microbe’s adaptation to nutrient-rich host-associated habitats, where it may interact with a variety of other microbial species. Understanding the metabolic and ecological roles of Gardnerella vaginalis str. KA00225 can provide insights into its contributions to the health and stability of the vaginal microbiome, as well as its potential implications for female reproductive health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusGardnerella
SpeciesGardnerella vaginalis
StrainKA00225

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Gardnerella vaginalis str. KA00225
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa, Oryctolagus cuniculus
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Gardnerella vaginalis strain KA00225 Contig_52, whole genome

Gene Summary

Adenine Count

475540 bp

Thymine Count

512835 bp

Guanine Count

368873 bp

Cytosine Count

312550 bp

Genome Length

1670019 bp

Protein-coding Genes

1181 genes

Non-Coding Genes

90 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
acetolactate synthase large subunitBFS05_00145Not AvailablePositive44036 - 4582965340.5
5-(carboxyamino)imidazole ribonucleotide synthaseBFS05_00150Not AvailableNegative45996 - 4716842878.2
5-(carboxyamino)imidazole ribonucleotide mutaseBFS05_00155Not AvailableNegative47152 - 4764917440.0
Trna-argNot AvailableNot AvailablePositive47743 - 47815Not Available
transcriptional repressorBFS05_00165Not AvailableNegative47898 - 4829615125.9
arylsulfataseBFS05_00170Not AvailableNegative48645 - 5087384518.4
mfs transporterBFS05_00175Not AvailablePositive51188 - 5257650545.5
hypothetical proteinBFS05_00180Not AvailablePositive52579 - 5520697947.5
16s ribosomal rnaNot AvailableNot AvailablePositive54624 - 56159Not Available
phosphoribosylamine--glycine ligaseBFS05_00185Not AvailableNegative55387 - 5665845421.8

Displaying genes 91 – 100 of 1271 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Pyogenic osteomyelitisCausesPMC7852921
Bacterial vaginosisCausesPMC11597594
Bacterial vaginosisCausesPMC11782042
UtisCausesPMC11782042
Bacterial vaginosisCausesPMC12054147
BvCausesPMC12519793
BvCausesPMC12800088
Bacterial vaginosisCausesPMC13228082
BvCausesPMC13228082
Bacterial vaginosisCausesPMC12281154

Displaying health effects 1 – 10 of 11 in total