Mobiluncus curtisii

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Actinomycetales

Family

Actinomycetaceae

Genus

Mobiluncus

Description

Mobiluncus curtisii is a gram-negative, curved rod-shaped bacterium that thrives in anaerobic environments, displaying a temperature preference for mesophilic conditions. As a heterotroph, it primarily derives its nutrients through the consumption of organic compounds. This microbe is commonly found in the human microbiota, particularly associated with various body sites, including the vagina, where it plays a role in the complex microbial community. The gram-negative characteristic of M. curtisii indicates that it has a thinner peptidoglycan layer surrounded by an outer membrane, which renders it less susceptible to certain antibiotics and contributes to its survival in hostile environments. Its unique curved rod shape is an adaptation that aids in motility, allowing the bacterium to navigate through viscous environments such as mucus. As a mesophilic organism, it thrives optimally at moderate temperatures, roughly between 30°C and 37°C, typical of human body temperatures.Being classified as a heterotroph, M. curtisii relies on organic compounds for energy, utilizing substances from the host's metabolic processes. Its anaerobic nature indicates that it does not require oxygen for growth, instead thriving in low-oxygen environments, such as the vaginal canal, where it may contribute to maintaining a stable microbial ecosystem.Mobiluncus curtisii has been implicated in bacterial vaginosis, a condition characterized by an imbalance in the vaginal microbiota. This bacterium's presence can indicate dysbiosis, which may lead to various health complications. Furthermore, M. curtisii demonstrates a fascinating symbiotic relationship with other microorganisms, contributing to the intricate balance of the human microbiome. Understanding this bacterium's role can shed light on broader implications for female reproductive health and its connection to systemic conditions.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderActinomycetales
FamilyActinomycetaceae
GenusMobiluncus
SpeciesMobiluncus curtisii
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Mobiluncus curtisii
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Mobiluncus curtisii strain NCTC11820 genome assembly, contig:

Gene Summary

Adenine Count

544999 bp

Thymine Count

547454 bp

Guanine Count

680866 bp

Cytosine Count

675055 bp

Genome Length

2448374 bp

Protein-coding Genes

2201 genes

Non-Coding Genes

119 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
AttlNot AvailableNot AvailablePositive1229619 - 1229630Not Available
Abc transporterNCTC11820_01061Not AvailableNegative1231904 - 123362261448.7
Imp dehydrogenase/gmp reductaseNCTC11820_01062Not AvailableNegative1233619 - 123473739680.6
queuine trna-ribosyltransferaseNCTC11820_01063Not AvailableNegative1234818 - 123613148592.6
Hypothetical proteinNCTC11820_01064Not AvailableNegative1236188 - 123692826437.0
Dna polymerase iii subunitNCTC11820_01065Not AvailableNegative1236975 - 123769726923.2
Gmp reductaseNCTC11820_01066Not AvailableNegative1237741 - 123927654956.1
Whib-like regulatory proteinNCTC11820_01067Not AvailablePositive1239538 - 123982810794.5
n(g),n(g)-dimethylarginine dimethylaminohydrolaseNCTC11820_01068Not AvailableNegative1240006 - 124082429874.7
uncharacterised proteinNCTC11820_01069Not AvailablePositive1240928 - 124122110889.3

Displaying genes 1 – 10 of 2320 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.