Rothia dentocariosa

Gram-positiveCocciNon-motileAerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Micrococcales

Family

Micrococcaceae

Genus

Rothia

Description

Rothia dentocariosa is a gram-positive, spherical-shaped microbe that thrives in mesophilic temperatures, categorized as a chemoheterotroph, and can be found in various body sites, including the oral cavity, respiratory tract, and gastrointestinal tract, across multiple species. As a chemoheterotroph, R. dentocariosa relies on organic compounds for energy and carbon, breaking down complex molecules to sustain its growth. This microbe is a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments, which allows it to adapt to different ecological niches. The gram-positive cell wall of R. dentocariosa provides structural support and maintains its spherical shape, while its mesophilic temperature preference enables it to grow optimally at temperatures between 20-45°C. As a facultative anaerobe, R. dentocariosa can switch between aerobic and anaerobic respiration, depending on the availability of oxygen. Its presence in various body sites across multiple species highlights its ability to colonize and thrive in diverse environments. R. dentocariosa has been implicated in several human diseases, including endocarditis and septicemia, and has also been found to produce antimicrobial compounds that inhibit the growth of other bacteria, making it a subject of ongoing research in the fields of microbiology and medicine.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMicrococcales
FamilyMicrococcaceae
GenusRothia
SpeciesRothia dentocariosa
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Rothia dentocariosa
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Struthio camelus
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Rothia dentocariosa strain OG2-1 NODE_86_length_206_cov_0.754967,

Gene Summary

Adenine Count

573273 bp

Thymine Count

571085 bp

Guanine Count

666748 bp

Cytosine Count

658797 bp

Genome Length

2469903 bp

Protein-coding Genes

2048 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nrdh-redoxinCRM92_10225Not AvailablePositive2364637 - 236494211255.1
shikimate 5-dehydrogenaseCRM92_10230Not AvailablePositive2364962 - 236578028729.4
rhomboid family intramembrane serine proteaseCRM92_10235Not AvailableNegative2366143 - 236692829562.3
peptidylprolyl isomeraseCRM92_10240Not AvailableNegative2367058 - 236758519061.7
hypothetical proteinCRM92_10245Not AvailablePositive2367804 - 236814512387.6
hypothetical proteinCRM92_10250Not AvailableNegative2368291 - 236868014037.6
Trna-alaNot AvailableNot AvailablePositive2369121 - 2369193Not Available
tat (twin-arginine translocation) pathway signal sequenceCRM92_10265Not AvailableNegative2369277 - 237032038492.4
duf3349 domain-containing proteinCRM92_10270Not AvailableNegative2370538 - 237102318092.2
hypothetical proteinCRM92_10275Not AvailableNegative2371071 - 237137310701.3

Displaying genes 4111 – 4120 of 4210 in total

Metabolites

10 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014140EnterolactoneC18H18O4Chemical structure of EnterolactoneNULL
Average298.338Da
Monoisotopic298.12050906Da
BASm0014170SaccharinC7H5NO3SChemical structure of SaccharinNULL
Average183.185Da
Monoisotopic182.999013721Da
BASm0014209EpicatechinC15H14O6Chemical structure of EpicatechinNULL
Average290.2681Da
Monoisotopic290.07903818Da
BASm00142945alpha-Androstan-3beta,17alpha-diol monosulfateC19H32O6SChemical structure of 5alpha-Androstan-3beta,17alpha-diol monosulfateNULL
Average388.52Da
Monoisotopic388.193057084Da
BASm0014317PhenylacetylglutamineC13H16N2O4Chemical structure of PhenylacetylglutamineNULL
Average264.2771Da
Monoisotopic264.11100701Da
BASm00143251-Margaroyl-glycerolC20H40O4Chemical structure of 1-Margaroyl-glycerolNULL
Average344.536Da
Monoisotopic344.292659768Da
BASm0014329Ursodeoxycholate sulfateC24H40O7SNot availableNULL
Average472.64Da
Monoisotopic472.249474802Da
BASm0014346Deoxycholic acid sulfateC24H40O7SNot availableNULL
Average472.64Da
Monoisotopic472.249474802Da
BASm0039676Clostridium nexileNot availableNot availableNot available
BASm0039735Streptococcus anginosusNot availableNot availableNot available

Displaying 1–10 of 10 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC10417112
EndocarditisCausesPMC10417112
SepticemiaCausesPMC10417112
Subacute bacterial endocarditisCausesPMC7934739
Mycotic brain aneurysmCausesPMC7934739
EndocarditisCausesPMC7934739
Dental plaquesCausesPMC8548776
Periodontal diseaseCausesPMC8548776

Displaying health effects 1 – 8 of 8 in total