Mycolicibacterium fortuitum

RodNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Mycobacteriales

Family

Mycobacteriaceae

Genus

Mycolicibacterium

Description

Mycolicibacterium fortuitum is a Gram-positive, rod-shaped bacterium classified as a mesophile, thriving optimally at moderate temperatures. This organism is a chemoheterotroph, relying on organic compounds for growth, and is categorized as a facultative anaerobe, meaning it can survive in both aerobic and anaerobic environments. Mycolicibacterium fortuitum can be found in a variety of body sites, including the skin, respiratory tract, and in some cases, the gastrointestinal tract, demonstrating its opportunistic nature. As a Gram-positive bacterium, Mycolicibacterium fortuitum possesses a thick peptidoglycan layer in its cell wall, which retains violet dye during the Gram staining process, distinguishing it from Gram-negative organisms. This structural characteristic contributes to its resilience and ability to survive in diverse environments, including soil and water, where it commonly resides as a free-living microbe. Being a mesophile, it prefers temperatures around 30-37°C, which aligns with human body temperature, enhancing its potential as a pathogen, particularly in immunocompromised individuals. Its classification as a chemoheterotroph underscores its dependence on organic substrates for energy and carbon, engaging in metabolic processes that can sometimes lead to opportunistic infections. M. fortuitum is notable for its ability to cause infections, including skin and soft tissue infections, particularly following trauma or surgery. It is often associated with contaminated medical equipment and can be resistant to several antibiotics, complicating treatment options. Its environmental ubiquity and adaptability underscore the importance of maintaining strict hygiene practices in clinical settings to prevent its transmission.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderMycobacteriales
FamilyMycobacteriaceae
GenusMycolicibacterium
SpeciesMycolicibacterium fortuitum
StrainNo strain

Profile

Physiology
Gram staining propertiesNot Available
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatSoil
Biotic relationshipNot Available
Host(s)Homo sapiens, Bos, Metazoa
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Mycolicibacterium fortuitum strain 852002-51695_SCH5383401

Gene Summary

Adenine Count

1178613 bp

Thymine Count

1177016 bp

Guanine Count

2285519 bp

Cytosine Count

2285213 bp

Genome Length

6926361 bp

Protein-coding Genes

6438 genes

Non-Coding Genes

95 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinA5751_00395Not AvailablePositive15488 - 1630628441.7
hypothetical proteinA5751_00400L8F618Negative16286 - 1740140084.3
hypothetical proteinA5751_00405Not AvailableNegative17638 - 1839028400.3
hypothetical proteinA5751_05900Not AvailablePositive19018 - 1928410037.1
hypothetical proteinA5751_05905Not AvailablePositive19754 - 2011312104.5
hypothetical proteinA5751_05910P35883Negative20138 - 203507421.02
hypothetical proteinA5751_05915Not AvailableNegative20369 - 2124631006.3
hypothetical proteinA5751_05925Not AvailableNegative22189 - 2255113659.3
hypothetical proteinA5751_05935Not AvailableNegative24204 - 2460513688.8
Ncrna_class:rnase_p_rnaNot AvailableNot AvailablePositive25038 - 25431Not Available

Displaying genes 61 – 70 of 19903 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

813 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002543-hydroxy-2-methylpropanoateC4H7O3Chemical structure of 3-hydroxy-2-methylpropanoateNot available
Average103.098Da
Monoisotopic103.0400677Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da

Displaying 1–10 of 813 metabolites

Health Effects

Health ConditionRelationReference
Ntm-pdCausesPMC11100324
Granulomatous pneumoniaCausesPMC11405685
Mycobacterial diseasesCausesPMC5276850
EndocarditisCausesPMC7642850
Pulmonary infectionCausesPMC7678322
Chronic mastitisCausesPMC8941956
MycobacteriosisCausesPMC8941956
Atypical cutaneous mycobacteriosisCausesPMC8941956
Mycobacterial diseaseCausesPMC8941956
Cervical lymphadenitisCausesPMC10928384

Displaying health effects 1 – 10 of 15 in total