Arachnia propionica

Gram-positiveRodNon-motileAnaerobic

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Arachnia

Description

Pseudopropionibacterium propionicum is a gram-positive, rod-shaped bacterium classified as a mesophilic heterotroph and is an obligate anaerobe. This microbe thrives in environments devoid of oxygen, predominantly found in various anaerobic habitats, including the human gut and the oral cavity, but it can also be isolated from dairy products and soil. As a gram-positive organism, Pseudopropionibacterium propionicum retains the crystal violet stain used in the Gram staining procedure, appearing purple under a microscope. Its rod-like shape contributes to its ability to form clusters or chains, facilitating its survival in anaerobic conditions. Being mesophilic, it grows optimally at moderate temperatures, generally around 30-37°C, which aligns with the body temperatures found in many mammals, including humans. As a heterotroph, Pseudopropionibacterium propionicum requires organic compounds for growth, primarily utilizing carbohydrates and other organic substrates. This metabolic characteristic enables it to thrive in nutrient-rich environments such as the gastrointestinal tract. Its classification as an obligate anaerobe highlights its inability to survive in the presence of oxygen, as oxygen is toxic to its cellular processes. Pseudopropionibacterium propionicum plays a significant role in the fermentation process, particularly in dairy, as it is involved in the production of propionic acid, a key preservative and flavoring agent in certain cheeses, such as Emmental. Additionally, its presence in the human microbiome contributes to maintaining gut health and balance by participating in the complex interplay of microbial communities. This bacterium's unique metabolic pathways and adaptations to anaerobic environments make it a fascinating subject of study in microbiology and food science.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusArachnia
SpeciesArachnia propionica
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Arachnia propionica
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobic
Optimal temperatureNot Available
Temperature rangeNot Available
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Arachnia propionica strain OH887_COT-365 scaffold_76, whole genome

Gene Summary

Adenine Count

551230 bp

Thymine Count

547715 bp

Guanine Count

1153236 bp

Cytosine Count

1146296 bp

Genome Length

3404168 bp

Protein-coding Genes

3021 genes

Non-Coding Genes

84 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
guanylate kinaseEL272_RS07760Not AvailableNegative1748070 - 174863320734.9
integration host factor, actinobacterial typeEL272_RS07765Not AvailableNegative1748747 - 174905811426.9
orotidine-5'-phosphate decarboxylaseEL272_RS07770Not AvailableNegative1749179 - 174997327226.7
quinone-dependent dihydroorotate dehydrogenaseEL272_RS07775Not AvailableNegative1749970 - 175102236811.5
carbamoyl-phosphate synthase large subunitEL272_RS07780Not AvailableNegative1751019 - 1754321118215.0
glutamine-hydrolyzing carbamoyl-phosphate synthase small subunitEL272_RS07785Not AvailableNegative1754372 - 175549940387.8
transcription antitermination factor nusbEL272_RS07790Not AvailableNegative1755519 - 175594415487.5
elongation factor pEL272_RS07795Not AvailableNegative1755937 - 175650020914.7
3-dehydroquinate synthaseEL272_RS07800Not AvailableNegative1756557 - 175764237722.4
shikimate kinaseEL272_RS07805Not AvailableNegative1757639 - 175813617824.5

Displaying genes 4671 – 4680 of 6164 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

14 records
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da
BASm0034745glycodeoxycholic acidC26H43NO5Chemical structure of glycodeoxycholic acidNULL
Average449.632Da
Monoisotopic449.314123489Da
BASm0039676Clostridium nexileNot availableNot availableNot available
BASm0039735Streptococcus anginosusNot availableNot availableNot available
BASm0040248[Clostridium] leptum DSM 753Not availableNot availableNot available
BASm0040447Pseudomonas fragiNot availableNot availableNot available
BASm0040476Penicillium echinulatumNot availableNot availableNot available
BASm0040485Lachnoanaerobaculum sp. ICM7Not availableNot availableNot available
BASm0040685Methylobacter tundripaludumNot availableNot availableNot available
BASm0040713Mobiluncus mulierisNot availableNot availableNot available

Displaying 1–10 of 14 metabolites

Health Effects

Health ConditionRelationReference
Thoracic actinomycosisCausesPMC6956836
Empyema necessitansCausesPMC6956836
Chronic, granulomatous infectionCausesPMC6956836
ActinomycosisCausesPMC6956836

Displaying health effects 1 – 4 of 4 in total