Cutibacterium acnes str. 11-78

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Propionibacteriales

Family

Propionibacteriaceae

Genus

Cutibacterium

Description

Cutibacterium acnes strain 11-78 is a Gram-positive, nonsporulating rod-shaped bacterium that thrives in anaerobic environments, with an optimal growth temperature of 37.0 °C. This microbe is primarily associated with host organisms, suggesting a specific relationship with its host environment, which is typical for many members of the Cutibacterium genus. C. acnes is known for its role in the human microbiome, particularly on the skin, where it can contribute to the maintenance of skin health as well as being implicated in various skin conditions. Its anaerobic nature indicates that it metabolizes substrates in the absence of oxygen, a trait that aligns with its ecological niche on human skin and within hair follicles. The ability to survive and proliferate at the human body temperature further underscores its adaptation to a host-associated lifestyle. The ecological role of C. acnes str. 11-78 may extend beyond mere commensalism, as it may play a crucial role in skin homeostasis by outcompeting pathogenic organisms and contributing to the skin's microbial diversity. Understanding the specific interactions and functions of this strain within the host microbiome could provide insights into its potential influence on skin health and disease.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderPropionibacteriales
FamilyPropionibacteriaceae
GenusCutibacterium
SpeciesCutibacterium acnes
Strain11-78

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Cutibacterium acnes str. 11-78
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Cutibacterium acnes strain 11-78 plasmid p11_78, whole genome

Gene Summary

Adenine Count

10090 bp

Thymine Count

10211 bp

Guanine Count

16891 bp

Cytosine Count

16841 bp

Genome Length

54033 bp

Protein-coding Genes

73 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dimethyl sulfoxide reductaseB1B09_04115Not AvailablePositive817458 - 81846836879.5
molybdopterin-guanine dinucleotide biosynthesis proteinB1B09_04120Not AvailableNegative818532 - 81883711080.2
molybdenum cofactor biosynthesis proteinB1B09_04125Not AvailableNegative818977 - 81947716780.2
molybdopterin-guanine dinucleotide biosynthesis protein aB1B09_04130Not AvailableNegative819774 - 82039421914.4
hypothetical proteinB1B09_04135Not AvailableNegative820445 - 82074411294.9
mfs transporterB1B09_04140Not AvailablePositive820737 - 82195143646.4
nitrate reductase subunit alphaB1B09_04145Not AvailablePositive822009 - 825746138101.0
nitrate reductase subunit betaB1B09_04150Not AvailablePositive825746 - 82726956567.6
nitrate reductase molybdenum cofactor assembly chaperoneB1B09_04155Not AvailablePositive827352 - 82794221680.0
respiratory nitrate reductase subunit gammaB1B09_04160Not AvailablePositive827939 - 82865226890.2

Displaying genes 871 – 880 of 2543 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Acute bacterial meningitisCausesPMC6306750
Thoracic actinomycosisCausesPMC6956836
AcneCausesPMC7808774
Epithelial ovarian cancerCausesPMC10587687
AcneCausesPMC13314309
Infectious complications after vertebroplasty/kyphoplastyCausesPMC7379344
Common acneCausesPMC3388012
AcneCausesPMC8549750

Displaying health effects 1 – 8 of 8 in total