Bifidobacterium breve str. DRBB28

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve str. DRBB28 is a Gram-positive, anaerobic bacterium primarily found in the gastrointestinal tracts of humans, particularly within the microbiota of healthy newborns and infants. This strain is notably present in human breast milk and the infant gut, where it plays a crucial role in the establishment and maintenance of a balanced gut microbiota during early development. As an anaerobe, Bifidobacterium breve str. DRBB28 thrives in oxygen-deprived environments, which are characteristic of the intestinal milieu. Its presence in breast milk suggests a potential nutritional and protective benefit, as this bacterium may contribute to the initial colonization of the infant gut, thereby influencing gut health and immune development. The unique ecological insight of Bifidobacterium breve str. DRBB28 is its association with the infant gut microbiota, where it may facilitate the digestion of lactose and other carbohydrates, contributing to the overall metabolic functions of the gut. This may also have implications for the prevention of gastrointestinal disorders in early life, highlighting the importance of this microbial species in the context of infant nutrition and health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainDRBB28

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve str. DRBB28
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain DRBB28 chromosome, complete genome.

Gene Summary

Adenine Count

507010 bp

Thymine Count

503119 bp

Guanine Count

722707 bp

Cytosine Count

729334 bp

Genome Length

2462170 bp

Protein-coding Genes

2048 genes

Non-Coding Genes

161 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
alpha/beta hydrolaseDRBB28_RS10930Not AvailableNegative2391427 - 239218527640.4
hypothetical proteinDRBB28_RS10935Not AvailableNegative2392243 - 239311230383.5
dctp deaminaseDRBB28_RS10940Not AvailablePositive2393469 - 239405021491.3
fivar domain-containing proteinDRBB28_RS10945Not AvailablePositive2394113 - 239549247347.1
cation-translocating p-type atpaseDRBB28_RS10950Not AvailableNegative2395582 - 2398572105553.0
substrate-binding domain-containing proteinDRBB28_RS10955Not AvailablePositive2398733 - 23989487561.19
pts glucose transporter subunit iiaDRBB28_RS10960Not AvailableNegative2398941 - 239945316796.1
n-acetylglucosamine-specific pts transporter subunit iibcDRBB28_RS10965Not AvailableNegative2399563 - 240110154410.2
mdr family mfs transporterDRBB28_RS10970Not AvailableNegative2401403 - 240261742738.4
23s rrna (guanosine(2251)-2'-o)-methyltransferase rlmbDRBB28_RS10975Not AvailablePositive2402705 - 240370335333.4

Displaying genes 2151 – 2160 of 2209 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.