Bifidobacterium breve str. DRBB28

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve str. DRBB28 is a Gram-positive, anaerobic bacterium primarily found in the gastrointestinal tracts of humans, particularly within the microbiota of healthy newborns and infants. This strain is notably present in human breast milk and the infant gut, where it plays a crucial role in the establishment and maintenance of a balanced gut microbiota during early development. As an anaerobe, Bifidobacterium breve str. DRBB28 thrives in oxygen-deprived environments, which are characteristic of the intestinal milieu. Its presence in breast milk suggests a potential nutritional and protective benefit, as this bacterium may contribute to the initial colonization of the infant gut, thereby influencing gut health and immune development. The unique ecological insight of Bifidobacterium breve str. DRBB28 is its association with the infant gut microbiota, where it may facilitate the digestion of lactose and other carbohydrates, contributing to the overall metabolic functions of the gut. This may also have implications for the prevention of gastrointestinal disorders in early life, highlighting the importance of this microbial species in the context of infant nutrition and health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainDRBB28

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve str. DRBB28
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain DRBB28 chromosome, complete genome.

Gene Summary

Adenine Count

507010 bp

Thymine Count

503119 bp

Guanine Count

722707 bp

Cytosine Count

729334 bp

Genome Length

2462170 bp

Protein-coding Genes

2048 genes

Non-Coding Genes

161 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
peptide deformylaseDRBB28_RS06580Not AvailableNegative1405309 - 140579418268.9
amp-dependent synthetase/ligaseDRBB28_RS06585Not AvailableNegative1405801 - 140786174615.4
hypothetical proteinDRBB28_RS06590Not AvailableNegative1407937 - 140842518429.7
guab3 family imp dehydrogenase-related proteinDRBB28_RS06595Not AvailableNegative1408571 - 140969539516.1
nadp-dependent isocitrate dehydrogenaseDRBB28_RS06600Not AvailablePositive1409824 - 141104445436.8
substrate-binding domain-containing proteinDRBB28_RS06605Not AvailablePositive1411185 - 141287058853.8
m23 family metallopeptidaseDRBB28_RS06610Not AvailableNegative1412883 - 141350622716.5
Trna-asnNot AvailableNot AvailablePositive1413743 - 1413818Not Available
tyrosine-type recombinase/integraseDRBB28_RS06620Not AvailablePositive1414098 - 141503335292.7
hypothetical proteinDRBB28_RS06625Not AvailableNegative1415090 - 141541611882.8

Displaying genes 1301 – 1310 of 2209 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.