Bifidobacterium breve str. DRBB28

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve str. DRBB28 is a Gram-positive, anaerobic bacterium primarily found in the gastrointestinal tracts of humans, particularly within the microbiota of healthy newborns and infants. This strain is notably present in human breast milk and the infant gut, where it plays a crucial role in the establishment and maintenance of a balanced gut microbiota during early development. As an anaerobe, Bifidobacterium breve str. DRBB28 thrives in oxygen-deprived environments, which are characteristic of the intestinal milieu. Its presence in breast milk suggests a potential nutritional and protective benefit, as this bacterium may contribute to the initial colonization of the infant gut, thereby influencing gut health and immune development. The unique ecological insight of Bifidobacterium breve str. DRBB28 is its association with the infant gut microbiota, where it may facilitate the digestion of lactose and other carbohydrates, contributing to the overall metabolic functions of the gut. This may also have implications for the prevention of gastrointestinal disorders in early life, highlighting the importance of this microbial species in the context of infant nutrition and health.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainDRBB28

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve str. DRBB28
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain DRBB28 chromosome, complete genome.

Gene Summary

Adenine Count

507010 bp

Thymine Count

503119 bp

Guanine Count

722707 bp

Cytosine Count

729334 bp

Genome Length

2462170 bp

Protein-coding Genes

2048 genes

Non-Coding Genes

161 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
nad(p) transhydrogenase subunit alphaDRBB28_RS05455Not AvailablePositive1196839 - 119800239698.2
nad(p) transhydrogenase subunit alphaDRBB28_RS05460Not AvailablePositive1198018 - 119832310627.5
nad(p)(+) transhydrogenase (re/si-specific) subunit betaDRBB28_RS05465Not AvailablePositive1198323 - 119974749106.1
ofa family mfs transporterDRBB28_RS05470Not AvailableNegative1199854 - 120113745707.9
50s ribosomal protein l25/general stress protein ctcDRBB28_RS05475Not AvailablePositive1201535 - 120216422308.6
branched-chain amino acid aminotransferaseDRBB28_RS05480Not AvailablePositive1202388 - 120351541490.2
mazg family proteinDRBB28_RS05485Not AvailablePositive1203714 - 120459532010.8
trimeric intracellular cation channel family proteinDRBB28_RS05490Not AvailablePositive1204944 - 120571427570.2
30s ribosomal protein s20DRBB28_RS05495Not AvailableNegative1205965 - 12062258930.93
translation elongation factor 4DRBB28_RS05500Not AvailablePositive1206372 - 120825269280.3

Displaying genes 1111 – 1120 of 2209 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.