Bifidobacterium breve str. BBRI4

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve str. BBRI4 is a Gram-positive anaerobic bacterium predominantly found in the gastrointestinal tracts of humans, particularly in the intestines of healthy newborns and infants. This strain is commonly associated with human breast milk and contributes significantly to the gut microbiota of infants, playing a vital role in the early stages of microbial colonization and gut development. As a member of the Bifidobacterium genus, B. breve str. BBRI4 is known for its ability to ferment carbohydrates, producing beneficial short-chain fatty acids that are essential for gut health. The presence of this strain in breast milk suggests a symbiotic relationship, where maternal milk supports the establishment of a healthy gut microbiota in infants, potentially influencing their immune system and metabolic processes. Further research into Bifidobacterium breve str. BBRI4 may reveal additional insights into its specific functional contributions to the infant gut microbiome and its potential protective effects against gastrointestinal disorders. Understanding the dynamics of this strain within the infant gut ecosystem could enhance our knowledge of early microbial health and inform strategies for improving infant nutrition and well-being.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainBBRI4

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve str. BBRI4
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain BBRI4 BBRI4_C28, whole genome shotgun

Gene Summary

Adenine Count

498596 bp

Thymine Count

503149 bp

Guanine Count

713268 bp

Cytosine Count

711705 bp

Genome Length

2426720 bp

Protein-coding Genes

2054 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sodium:proton antiporterBBRI4_1c20A8FHE3Positive25057 - 2712975807.8
permeaseBBRI4_1c21O32134Negative27171 - 2797427972.3
phospholipase/carboxylesteraseBBRI4_1c22Not AvailableNegative28086 - 2884427593.3
hypothetical proteinBBRI4_1c23Not AvailableNegative28902 - 2977130385.4
deoxycytidine triphosphate deaminaseBBRI4_1c24B3DP64Positive30128 - 3070921397.1
hypothetical proteinBBRI4_1c25Not AvailablePositive30775 - 3210345681.2
haloacid dehalogenaseBBRI4_1c26P37278Negative32193 - 35183105567.0
transcriptional regulatorBBRI4_1c27Not AvailablePositive35343 - 355587561.19
pts n-acetylglucosamine transporter subunit iiabcBBRI4_1c28Not AvailableNegative35551 - 3606316796.1
pts n-acetylglucosamine transporter subunit iiabcBBRI4_1c29P09323Negative36173 - 3771154357.1

Displaying genes 41 – 50 of 2122 in total

Metabolites

116 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm00007052-dehydro-3-deoxy-D-arabinonateC5H7O5Chemical structure of 2-dehydro-3-deoxy-D-arabinonateNot available
Average147.107Da
Monoisotopic147.0298969Da
BASm0000738D-lyxoseC5H10O5Chemical structure of D-lyxose1114-34-7
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000848hexanoateC6H11O2Chemical structure of hexanoateNot available
Average115.1503Da
Monoisotopic115.075904596Da
BASm0001111keto-D-tagaturonateC6H9O7Chemical structure of keto-D-tagaturonateNot available
Average193.132Da
Monoisotopic193.0353762Da

Displaying 1–10 of 116 metabolites

Health Effects

No health effects information available for this bacterium.