Bifidobacterium breve

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve is a Gram-positive, rod-shaped microbe that thrives in mesophilic temperatures, categorized as a Chemoheterotroph, and can be found in various body sites across all species, including the gut, respiratory, and urinary tracts, and is an Obligate Anaerobe. As a Gram-positive microbe, Bifidobacterium breve has a thick peptidoglycan layer in its cell wall, providing it with a strong defense against environmental stresses. Its rod-shaped morphology allows it to adapt to different environments and interact with various surfaces. The mesophilic temperature preference of Bifidobacterium breve enables it to grow and multiply in temperatures ranging from 20-45°C, making it suitable for human and animal hosts. As a Chemoheterotroph, Bifidobacterium breve relies on organic compounds for energy and carbon sources, breaking down complex molecules into simpler ones to sustain its growth. Its presence in various body sites suggests its ability to colonize and thrive in diverse environments. The Obligate Anaerobe nature of Bifidobacterium breve means it requires the absence of oxygen to survive, which is why it is typically found in areas with low oxygen levels, such as the gut. Bifidobacterium breve plays a crucial role in maintaining the balance of the microbiome and has been shown to have probiotic properties, aiding in digestion and immune system function. It has also been found to produce antimicrobial compounds that inhibit the growth of pathogenic bacteria, making it a valuable microbe in the prevention and treatment of various diseases.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve , Complete Genome

Gene Summary

Adenine Count

473596 bp

Thymine Count

472816 bp

Guanine Count

671214 bp

Cytosine Count

671285 bp

Genome Length

2288919 bp

Protein-coding Genes

1770 genes

Non-Coding Genes

60 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
two-component sensor histidine kinaseCJ196_00885Not AvailablePositive208071 - 20936646651.3
dna-binding response regulatorCJ196_00890Not AvailablePositive209419 - 21018928812.0
phosphate abc transporter substrate-binding protein pstsCJ196_00895Not AvailablePositive210443 - 21157339204.4
phosphate abc transporter permease subunit pstcCJ196_00900Not AvailablePositive211780 - 21273333746.2
phosphate abc transporter, permease protein pstaCJ196_00905Not AvailablePositive212766 - 21373134296.1
phosphate abc transporter atp-binding proteinCJ196_00910Not AvailablePositive213777 - 21455628826.2
ncs2 family permeaseCJ196_00915Not AvailableNegative215198 - 21659248775.6
hypothetical proteinCJ196_00920Not AvailablePositive216834 - 21762528521.4
acyl-coa dehydrogenaseCJ196_00925Not AvailableNegative217693 - 2179148083.53
50s ribosomal protein l10CJ196_00930Not AvailablePositive217913 - 21843418703.5

Displaying genes 251 – 260 of 3786 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.