Bifidobacterium breve str. 139W423

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve str. 139W423 is a Gram-positive, anaerobic bacterium predominantly found in the gastrointestinal tracts of healthy infants, particularly within the infant gut microbiota derived from human breast milk. This species plays a pivotal role in the establishment and maintenance of a healthy gut microbiome during early development. Bifidobacterium breve str. 139W423 thrives in anaerobic environments, such as those found in the intestines, where it contributes to the fermentation of dietary fibers and the production of beneficial short-chain fatty acids. Its presence in breast milk underscores its importance in maternal-infant health, as it is one of the primary microorganisms that colonize the infant gut, supporting immune development and potentially influencing metabolic processes. The ecological significance of Bifidobacterium breve str. 139W423 lies in its ability to adapt to the unique conditions of the human gut, particularly in infants, where it contributes to the establishment of a balanced microbiota that is essential for digestion and overall health. Through its interactions with other microbial species and its metabolic activities, Bifidobacterium breve str. 139W423 plays a crucial role in shaping the gut environment, underscoring the importance of early microbial colonization in the development of a resilient intestinal microbiome.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strain139W423

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve str. 139W423
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain 139W423 chromosome, complete genome.

Gene Summary

Adenine Count

498719 bp

Thymine Count

498434 bp

Guanine Count

706701 bp

Cytosine Count

707422 bp

Genome Length

2411276 bp

Protein-coding Genes

2027 genes

Non-Coding Genes

107 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
carbohydrate abc transporter permeaseBB139W423_RS08885Not AvailableNegative1977330 - 197830134780.0
abc transporter substrate-binding proteinBB139W423_RS08890Not AvailableNegative1978491 - 197980746169.2
Trna-serNot AvailableNot AvailablePositive1980070 - 1980157Not Available
serine--trna ligaseBB139W423_RS08900Not AvailableNegative1980280 - 198156648013.0
diacylglycerol/lipid kinase family proteinBB139W423_RS08905Not AvailablePositive1981806 - 198298742027.4
prd domain-containing proteinBB139W423_RS08910Not AvailableNegative1982989 - 198388232888.6
glucose pts transporter subunit iiaBB139W423_RS08915Not AvailableNegative1983934 - 198603973162.2
phosphoglucomutase (alpha-d-glucose-1,6-bisphosphate-dependent)BB139W423_RS08920Not AvailablePositive1986535 - 198821160215.6
hypothetical proteinBB139W423_RS08925Not AvailableNegative1988739 - 198980639577.7
rrf2 family transcriptional regulatorBB139W423_RS08930Not AvailablePositive1990003 - 199043415113.8

Displaying genes 1761 – 1770 of 2134 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.