Bifidobacterium breve str. 139W423

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve str. 139W423 is a Gram-positive, anaerobic bacterium predominantly found in the gastrointestinal tracts of healthy infants, particularly within the infant gut microbiota derived from human breast milk. This species plays a pivotal role in the establishment and maintenance of a healthy gut microbiome during early development. Bifidobacterium breve str. 139W423 thrives in anaerobic environments, such as those found in the intestines, where it contributes to the fermentation of dietary fibers and the production of beneficial short-chain fatty acids. Its presence in breast milk underscores its importance in maternal-infant health, as it is one of the primary microorganisms that colonize the infant gut, supporting immune development and potentially influencing metabolic processes. The ecological significance of Bifidobacterium breve str. 139W423 lies in its ability to adapt to the unique conditions of the human gut, particularly in infants, where it contributes to the establishment of a balanced microbiota that is essential for digestion and overall health. Through its interactions with other microbial species and its metabolic activities, Bifidobacterium breve str. 139W423 plays a crucial role in shaping the gut environment, underscoring the importance of early microbial colonization in the development of a resilient intestinal microbiome.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strain139W423

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve str. 139W423
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain 139W423 chromosome, complete genome.

Gene Summary

Adenine Count

498719 bp

Thymine Count

498434 bp

Guanine Count

706701 bp

Cytosine Count

707422 bp

Genome Length

2411276 bp

Protein-coding Genes

2027 genes

Non-Coding Genes

107 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional adp-dependent nad(p)h-hydrate dehydratase/nad(p)h-hydrate epimeraseBB139W423_RS05615Not AvailableNegative1270881 - 127264460657.9
abc-f family atp-binding cassette domain-containing proteinBB139W423_RS05620Not AvailablePositive1272816 - 127441758689.2
sdr family nad(p)-dependent oxidoreductaseBB139W423_RS05625Not AvailablePositive1274479 - 127518625481.2
duf3990 domain-containing proteinBB139W423_RS11680Not AvailableNegative1275252 - 12754346695.76
duf3990 domain-containing proteinBB139W423_RS11685Not AvailableNegative1275492 - 12755361783.22
atp-binding cassette domain-containing proteinBB139W423_RS11445Not AvailableNegative1275533 - 127595215221.0
duf3990 domain-containing proteinBB139W423_RS11690Not AvailableNegative1275952 - 127659722557.2
pyridoxal phosphate-dependent aminotransferaseBB139W423_RS05640Not AvailableNegative1276842 - 127803243203.2
excinuclease abc subunit uvraBB139W423_RS05645Not AvailablePositive1278228 - 1281257111549.0
excinuclease abc subunit uvrcBB139W423_RS05650Not AvailablePositive1281411 - 128382888907.8

Displaying genes 1161 – 1170 of 2134 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.