Bifidobacterium breve str. 139W423

Gram-positiveRodAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium breve str. 139W423 is a Gram-positive, anaerobic bacterium predominantly found in the gastrointestinal tracts of healthy infants, particularly within the infant gut microbiota derived from human breast milk. This species plays a pivotal role in the establishment and maintenance of a healthy gut microbiome during early development. Bifidobacterium breve str. 139W423 thrives in anaerobic environments, such as those found in the intestines, where it contributes to the fermentation of dietary fibers and the production of beneficial short-chain fatty acids. Its presence in breast milk underscores its importance in maternal-infant health, as it is one of the primary microorganisms that colonize the infant gut, supporting immune development and potentially influencing metabolic processes. The ecological significance of Bifidobacterium breve str. 139W423 lies in its ability to adapt to the unique conditions of the human gut, particularly in infants, where it contributes to the establishment of a balanced microbiota that is essential for digestion and overall health. Through its interactions with other microbial species and its metabolic activities, Bifidobacterium breve str. 139W423 plays a crucial role in shaping the gut environment, underscoring the importance of early microbial colonization in the development of a resilient intestinal microbiome.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium breve
Strain139W423

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Bifidobacterium breve str. 139W423
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbreast milk; gastrointestinal tract; gut; human breast milk; human gut; infant gut microbiota; infant intestine; intestines; microbiota of healthy newborns
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium breve strain 139W423 chromosome, complete genome.

Gene Summary

Adenine Count

498719 bp

Thymine Count

498434 bp

Guanine Count

706701 bp

Cytosine Count

707422 bp

Genome Length

2411276 bp

Protein-coding Genes

2027 genes

Non-Coding Genes

107 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
abc transporter permeaseBB139W423_RS05120Not AvailablePositive1167887 - 116910443345.2
abc transporter atp-binding proteinBB139W423_RS05125Not AvailablePositive1169106 - 117001432463.2
30s ribosomal protein s4BB139W423_RS05130Not AvailablePositive1170211 - 117083723660.6
gamma-glutamyl-gamma-aminobutyrate hydrolase family proteinBB139W423_RS05135Not AvailableNegative1171313 - 117209528409.8
cytidine deaminaseBB139W423_RS05140Not AvailableNegative1172233 - 117271817983.3
sdpi family proteinBB139W423_RS05145Not AvailablePositive1172809 - 117316512627.9
transglutaminase-like domain-containing proteinBB139W423_RS05150Not AvailablePositive1173270 - 117387222789.8
type ii toxin-antitoxin system pemk/mazf family toxinBB139W423_RS05155Not AvailableNegative1174049 - 117440513333.0
type ii toxin-antitoxin system relb/dinj family antitoxinBB139W423_RS05160Not AvailableNegative1174392 - 117468810998.1
histidine phosphatase family proteinBB139W423_RS05165Not AvailablePositive1174937 - 117561124581.5

Displaying genes 1061 – 1070 of 2134 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.