Bifidobacterium longum subsp. infantis str. BT1

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. infantis str. BT1 is a Gram-positive, rod-shaped bacterium that typically exists in clusters, pairs, or as single cells. This strain is classified as an anaerobe, thriving in environments devoid of oxygen, which aligns with its natural habitat associated with hosts, such as the gastrointestinal tract of infants. The optimal growth temperature for B. longum subsp. infantis str. BT1 is approximately 37.0°C, reflecting its adaptation to the warm environment of the human body. Bifidobacterium longum subsp. infantis plays a significant role in the gut microbiota, particularly during early life, where it contributes to the development of the immune system and digestion of human milk oligosaccharides. Its presence is crucial for maintaining gut health and homeostasis in infants. Notably, the ability of this strain to form various cell arrangements may enhance its adaptability and functionality within the complex microbial communities of the host's gut. In conclusion, Bifidobacterium longum subsp. infantis str. BT1 exemplifies a specialized adaptation to the host-associated environment, where its anaerobic nature and optimal growth temperature foster a symbiotic relationship, ultimately supporting the health and development of its human host.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. infantis BT1

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. infantis str. BT1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNon-pathogenic

Genome Summary

Bifidobacterium longum subsp. infantis strain BT1 chromosome,

Gene Summary

Adenine Count

522480 bp

Thymine Count

524486 bp

Guanine Count

768699 bp

Cytosine Count

762450 bp

Genome Length

2578115 bp

Protein-coding Genes

2236 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
50s ribosomal protein l34RY67_RS02975Not AvailableNegative733236 - 7333705377.74
chromosomal replication initiator protein dnaaRY67_RS02980Not AvailablePositive733689 - 73519155271.9
dna polymerase iii subunit betaRY67_RS02985Not AvailablePositive735926 - 73705040983.5
dna replication/repair protein recfRY67_RS02990Not AvailablePositive737078 - 73831644857.5
duf721 domain-containing proteinRY67_RS02995Not AvailablePositive738313 - 73878317584.2
dna topoisomerase (atp-hydrolyzing) subunit bRY67_RS03000Not AvailablePositive738916 - 74105478689.9
dna gyrase subunit aRY67_RS03005Not AvailablePositive741229 - 74390798973.0
duf3566 domain-containing proteinRY67_RS03010Not AvailablePositive743977 - 74454319762.8
atp-binding proteinRY67_RS03015Not AvailablePositive745189 - 74661053784.1
substrate-binding domain-containing proteinRY67_RS03020Not AvailableNegative746671 - 7468958036.54

Displaying genes 611 – 620 of 2304 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.