Bifidobacterium longum subsp. infantis str. BT1

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. infantis str. BT1 is a Gram-positive, rod-shaped bacterium that typically exists in clusters, pairs, or as single cells. This strain is classified as an anaerobe, thriving in environments devoid of oxygen, which aligns with its natural habitat associated with hosts, such as the gastrointestinal tract of infants. The optimal growth temperature for B. longum subsp. infantis str. BT1 is approximately 37.0°C, reflecting its adaptation to the warm environment of the human body. Bifidobacterium longum subsp. infantis plays a significant role in the gut microbiota, particularly during early life, where it contributes to the development of the immune system and digestion of human milk oligosaccharides. Its presence is crucial for maintaining gut health and homeostasis in infants. Notably, the ability of this strain to form various cell arrangements may enhance its adaptability and functionality within the complex microbial communities of the host's gut. In conclusion, Bifidobacterium longum subsp. infantis str. BT1 exemplifies a specialized adaptation to the host-associated environment, where its anaerobic nature and optimal growth temperature foster a symbiotic relationship, ultimately supporting the health and development of its human host.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. infantis BT1

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. infantis str. BT1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNon-pathogenic

Genome Summary

Bifidobacterium longum subsp. infantis strain BT1 chromosome,

Gene Summary

Adenine Count

522480 bp

Thymine Count

524486 bp

Guanine Count

768699 bp

Cytosine Count

762450 bp

Genome Length

2578115 bp

Protein-coding Genes

2236 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
argininosuccinate lyaseRY67_RS10790Not AvailableNegative2506678 - 250815053383.0
argininosuccinate synthaseRY67_RS10795Not AvailableNegative2508326 - 250956445552.8
arginine repressorRY67_RS10800Not AvailableNegative2509647 - 251015917745.1
ornithine carbamoyltransferaseRY67_RS10805Not AvailableNegative2510156 - 251112135442.9
acetylornithine transaminaseRY67_RS10810Not AvailableNegative2511165 - 251246045646.9
acetylglutamate kinaseRY67_RS10815Not AvailableNegative2512450 - 251340633848.0
bifunctional glutamate n-acetyltransferase/amino-acid acetyltransferase argjRY67_RS10820Not AvailableNegative2513543 - 251471839798.7
n-acetyl-gamma-glutamyl-phosphate reductaseRY67_RS10825Not AvailableNegative2514715 - 251580937978.2
hypothetical proteinRY67_RS10830Not AvailableNegative2515908 - 251659424540.5
phenylalanine--trna ligase subunit betaRY67_RS10835Not AvailableNegative2516625 - 251923494510.8

Displaying genes 2241 – 2250 of 2304 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.