Bifidobacterium longum subsp. infantis str. BT1

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. infantis str. BT1 is a Gram-positive, rod-shaped bacterium that typically exists in clusters, pairs, or as single cells. This strain is classified as an anaerobe, thriving in environments devoid of oxygen, which aligns with its natural habitat associated with hosts, such as the gastrointestinal tract of infants. The optimal growth temperature for B. longum subsp. infantis str. BT1 is approximately 37.0°C, reflecting its adaptation to the warm environment of the human body. Bifidobacterium longum subsp. infantis plays a significant role in the gut microbiota, particularly during early life, where it contributes to the development of the immune system and digestion of human milk oligosaccharides. Its presence is crucial for maintaining gut health and homeostasis in infants. Notably, the ability of this strain to form various cell arrangements may enhance its adaptability and functionality within the complex microbial communities of the host's gut. In conclusion, Bifidobacterium longum subsp. infantis str. BT1 exemplifies a specialized adaptation to the host-associated environment, where its anaerobic nature and optimal growth temperature foster a symbiotic relationship, ultimately supporting the health and development of its human host.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. infantis BT1

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. infantis str. BT1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNon-pathogenic

Genome Summary

Bifidobacterium longum subsp. infantis strain BT1 chromosome,

Gene Summary

Adenine Count

522480 bp

Thymine Count

524486 bp

Guanine Count

768699 bp

Cytosine Count

762450 bp

Genome Length

2578115 bp

Protein-coding Genes

2236 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
rna polymerase sigma factorRY67_RS08100Not AvailablePositive1925850 - 192723851953.4
dna gyrase/topoisomerase iv subunit bRY67_RS08105Not AvailablePositive1927296 - 192961184544.8
mfs transporterRY67_RS08110Not AvailablePositive1929778 - 193100443198.8
pfkb family carbohydrate kinaseRY67_RS08115Not AvailablePositive1931048 - 193164420306.9
dead/deah box helicaseRY67_RS08120Not AvailablePositive1931660 - 1936393171497.0
response regulator transcription factorRY67_RS08125Not AvailableNegative1936404 - 193719228170.4
dna gyrase/topoisomerase iv subunit aRY67_RS08130Not AvailableNegative1937337 - 194006697779.0
alkaline phosphatase family proteinRY67_RS08135Not AvailablePositive1940317 - 194158545547.6
septation protein sephRY67_RS08140Not AvailableNegative1941595 - 194268638987.8
duf4193 domain-containing proteinRY67_RS08145Not AvailablePositive1942845 - 194313810610.8

Displaying genes 1671 – 1680 of 2304 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.