Bifidobacterium longum subsp. infantis str. BT1

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. infantis str. BT1 is a Gram-positive, rod-shaped bacterium that typically exists in clusters, pairs, or as single cells. This strain is classified as an anaerobe, thriving in environments devoid of oxygen, which aligns with its natural habitat associated with hosts, such as the gastrointestinal tract of infants. The optimal growth temperature for B. longum subsp. infantis str. BT1 is approximately 37.0°C, reflecting its adaptation to the warm environment of the human body. Bifidobacterium longum subsp. infantis plays a significant role in the gut microbiota, particularly during early life, where it contributes to the development of the immune system and digestion of human milk oligosaccharides. Its presence is crucial for maintaining gut health and homeostasis in infants. Notably, the ability of this strain to form various cell arrangements may enhance its adaptability and functionality within the complex microbial communities of the host's gut. In conclusion, Bifidobacterium longum subsp. infantis str. BT1 exemplifies a specialized adaptation to the host-associated environment, where its anaerobic nature and optimal growth temperature foster a symbiotic relationship, ultimately supporting the health and development of its human host.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. infantis BT1

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. infantis str. BT1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNon-pathogenic

Genome Summary

Bifidobacterium longum subsp. infantis strain BT1 chromosome,

Gene Summary

Adenine Count

522480 bp

Thymine Count

524486 bp

Guanine Count

768699 bp

Cytosine Count

762450 bp

Genome Length

2578115 bp

Protein-coding Genes

2236 genes

Non-Coding Genes

68 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ispd/tari family cytidylyltransferaseRY67_RS04910Not AvailablePositive1168076 - 116895131306.0
pyroglutamyl-peptidase iRY67_RS04915Not AvailablePositive1168961 - 116963824324.9
cell division proteinRY67_RS04920Not AvailablePositive1169786 - 117134556261.2
c1 family peptidaseRY67_RS04925Not AvailablePositive1171460 - 117280350099.1
3-deoxy-7-phosphoheptulonate synthaseRY67_RS04930Not AvailablePositive1172975 - 117410841489.2
3-deoxy-7-phosphoheptulonate synthaseRY67_RS04935Not AvailablePositive1174237 - 117546944656.3
5'-methylthioadenosine/s-adenosylhomocysteine nucleosidaseRY67_RS04940Not AvailablePositive1175590 - 117630324878.6
mfs transporterRY67_RS04945Not AvailablePositive1176561 - 117787447097.5
sensor histidine kinaseRY67_RS04950Not AvailablePositive1178023 - 117940249187.8
response regulator transcription factorRY67_RS04955Not AvailablePositive1179586 - 118029026327.8

Displaying genes 1001 – 1010 of 2304 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.