Bifidobacterium longum subsp. longum str. VMKB44

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. longum str. VMKB44 is a Gram-positive, anaerobic bacterium characterized by its rod shape and tendency to form clusters, pairs, and singles. This strain optimally thrives at a temperature of 37.0°C, which aligns with the physiological temperature of its primary habitat, the human gut, where it resides as a host-associated microbe. As a member of the Bifidobacterium genus, B. longum subsp. longum str. VMKB44 is significant for its potential roles in gut health, including the fermentation of dietary fibers and production of short-chain fatty acids, which are beneficial for maintaining intestinal homeostasis. The strain's anaerobic nature suggests that it plays a critical role in maintaining the anaerobic environment typical of the gut microbiome, which is essential for the survival of various gut microorganisms and the overall health of the host. The ability of B. longum subsp. longum str. VMKB44 to form various cell arrangements may enhance its adaptability to different microenvironments within the gut, contributing to its ecological versatility. This adaptability could be vital not only for its survival but also for the modulation of the gut microbiota composition, thereby influencing host metabolic processes and immune responses. Understanding the specific functions and interactions of this strain within the gut ecosystem could provide insights into its role in promoting gut health and preventing dysbiosis.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. longum VMKB44

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. longum str. VMKB44
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Primates
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium longum subsp. longum strain VMKB44 seq35, whole

Gene Summary

Adenine Count

495880 bp

Thymine Count

497693 bp

Guanine Count

753975 bp

Cytosine Count

754291 bp

Genome Length

2501933 bp

Protein-coding Genes

2007 genes

Non-Coding Genes

102 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinNL89_02380Not AvailableNegative568476 - 56920425233.6
transcription elongation factor nusaNL89_02385Not AvailablePositive569412 - 57047938071.3
translation initiation factor if-2NL89_02390Not AvailablePositive570749 - 573676103975.0
ribosome-binding factor aNL89_02395Not AvailablePositive573827 - 57430017535.3
pseudouridine synthaseNL89_02400Not AvailablePositive574302 - 57546541809.6
fad synthaseNL89_02405Not AvailablePositive575563 - 57668741325.0
dna repair protein radaNL89_02410Not AvailableNegative576702 - 57824053543.6
hypothetical proteinNL89_02415Not AvailablePositive578368 - 57900022108.5
ribose 5-phosphate isomeraseNL89_02420Not AvailableNegative579434 - 58013225270.1
ribonuclease hNL89_02425Not AvailableNegative580263 - 58109929737.5

Displaying genes 511 – 520 of 2109 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.