Bifidobacterium longum subsp. longum str. VMKB44

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Actinomycetota

Class

Actinomycetes

Order

Bifidobacteriales

Family

Bifidobacteriaceae

Genus

Bifidobacterium

Description

Bifidobacterium longum subsp. longum str. VMKB44 is a Gram-positive, anaerobic bacterium characterized by its rod shape and tendency to form clusters, pairs, and singles. This strain optimally thrives at a temperature of 37.0°C, which aligns with the physiological temperature of its primary habitat, the human gut, where it resides as a host-associated microbe. As a member of the Bifidobacterium genus, B. longum subsp. longum str. VMKB44 is significant for its potential roles in gut health, including the fermentation of dietary fibers and production of short-chain fatty acids, which are beneficial for maintaining intestinal homeostasis. The strain's anaerobic nature suggests that it plays a critical role in maintaining the anaerobic environment typical of the gut microbiome, which is essential for the survival of various gut microorganisms and the overall health of the host. The ability of B. longum subsp. longum str. VMKB44 to form various cell arrangements may enhance its adaptability to different microenvironments within the gut, contributing to its ecological versatility. This adaptability could be vital not only for its survival but also for the modulation of the gut microbiota composition, thereby influencing host metabolic processes and immune responses. Understanding the specific functions and interactions of this strain within the gut ecosystem could provide insights into its role in promoting gut health and preventing dysbiosis.

Taxonomy

KingdomBacillati
PhylumActinomycetota
ClassActinomycetes
OrderBifidobacteriales
FamilyBifidobacteriaceae
GenusBifidobacterium
SpeciesBifidobacterium longum
Strainsubsp. longum VMKB44

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Bifidobacterium longum subsp. longum str. VMKB44
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Primates
Cell arrangementClusters - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Bifidobacterium longum subsp. longum strain VMKB44 seq35, whole

Gene Summary

Adenine Count

495880 bp

Thymine Count

497693 bp

Guanine Count

753975 bp

Cytosine Count

754291 bp

Genome Length

2501933 bp

Protein-coding Genes

2007 genes

Non-Coding Genes

102 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
threonine synthaseNL89_01095Not AvailableNegative268230 - 26972054066.0
serine hydroxymethyltransferaseNL89_01100Not AvailablePositive269943 - 27064425003.5
gamma-glutamyl phosphate reductaseNL89_01105Not AvailablePositive270766 - 27206145572.4
phosphoribosylglycinamide synthetaseNL89_01110Not AvailablePositive272058 - 27263921571.0
nicotinic acid mononucleotide adenylyltransferaseNL89_01115Not AvailablePositive272693 - 27342126717.5
beta-glucosidaseNL89_01120Not AvailableNegative273519 - 27472140864.3
hypothetical proteinNL89_01125Not AvailablePositive274894 - 278133116176.0
gnat family acetyltransferaseNL89_01130Not AvailablePositive278267 - 27880019526.2
peptidyl-trna hydrolaseNL89_01135Not AvailablePositive278960 - 27955921722.9
transcription-repair coupling factorNL89_01140Not AvailablePositive279549 - 283133131248.0

Displaying genes 261 – 270 of 2109 in total

Metabolites

1 record
Metabolite IDMetabolite nameStructureCAS number
BASm0014029(S)-3-Hydroxyisobutyric acidC19H35N5O6SeChemical structure of (S)-3-Hydroxyisobutyric acid26543-05-5
Average508.489Da
Monoisotopic509.175256Da

Displaying 1–1 of 1 metabolites

Health Effects

No health effects information available for this bacterium.