Clostridium perfringens str. JP838

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium perfringens str. JP838 is a Gram-positive, rod-shaped bacterium that typically exists in pairs, singles, or chains. This strain is classified as a chemoorganotroph, indicating that it derives energy from organic compounds. It thrives optimally at a temperature of 37.0 °C, which is consistent with its habitat as a host-associated microbe, suggesting a potential association with warm-blooded animals or humans. As an anaerobe, C. perfringens str. JP838 requires an environment devoid of oxygen for growth and metabolism. This trait is characteristic of many members of the Clostridium genus, which commonly inhabit the gastrointestinal tracts of various hosts. The ability to grow in anaerobic conditions may confer advantages in microbial competition within the gut environment, where oxygen levels are minimal. The ecological role of C. perfringens str. JP838 may involve participation in the degradation of organic matter in host-associated environments, potentially influencing gut health and microbial community dynamics. Understanding this strain's metabolic capabilities and interactions within its ecological niche could provide further insights into the functional roles of anaerobic bacteria in host-associated microbiomes.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium perfringens
StrainJP838

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridium perfringens str. JP838
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos
Cell arrangementPairs - Singles - Chains
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityAnimal; Human

Genome Summary

Clostridium perfringens strain JP838 plasmid pJFP838E, complete

Gene Summary

Adenine Count

4328 bp

Thymine Count

6274 bp

Guanine Count

1501 bp

Cytosine Count

2554 bp

Genome Length

14657 bp

Protein-coding Genes

14 genes

Non-Coding Genes

0 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
plasmid mobilization proteinJFP838_RS16020Not AvailableNegative988 - 130512629.5
copg family transcriptional regulatorJFP838_RS16025Not AvailableNegative1563 - 186811995.9
hypothetical proteinJFP838_RS16030Not AvailableNegative2169 - 341649602.8
hypothetical proteinJFP838_RS16035Not AvailableNegative3506 - 402120452.8
hlyd family efflux transporter periplasmic adaptor subunitJFP838_RS16040Not AvailableNegative4040 - 556958440.3
peptidase domain-containing abc transporterJFP838_RS16045Not AvailableNegative5559 - 776383257.3
hypothetical proteinJFP838_RS16050Not AvailablePositive7939 - 81276450.9
hypothetical proteinJFP838_RS19635Not AvailablePositive8169 - 83455911.19
helix-turn-helix domain-containing proteinJFP838_RS16060Not AvailableNegative8656 - 894611036.3
hypothetical proteinJFP838_RS16065Not AvailablePositive9229 - 94296344.72

Displaying genes 1 – 10 of 641 in total

Metabolites

6 records
Metabolite IDMetabolite nameStructureCAS number
BASm0001481plastoquinol-9C53H82O2Chemical structure of plastoquinol-9Not available
Average751.237Da
Monoisotopic750.6314819Da
BASm00056516-geranylgeranyl-2-methylbenzene-1,4-diolC27H40O2Chemical structure of 6-geranylgeranyl-2-methylbenzene-1,4-diolNot available
Average396.615Da
Monoisotopic396.302830528Da
BASm00056526-geranylgeranyl-2,3-dimethylbenzene-1,4-diolC28H42O2Chemical structure of 6-geranylgeranyl-2,3-dimethylbenzene-1,4-diolNot available
Average410.642Da
Monoisotopic410.3184806Da
BASm0014042Oxoglutaric acidC5H6O5Chemical structure of Oxoglutaric acid328-50-7
Average146.0981Da
Monoisotopic146.021523302Da
BASm00141964-Hydroxyphenylpyruvic acidC9H8O4Chemical structure of 4-Hydroxyphenylpyruvic acidNULL
Average180.1574Da
Monoisotopic180.042258744Da
BASm00200002-trans,6-trans,10-trans-Geranylgeranyl diphosphateC20H36O7P2Chemical structure of 2-trans,6-trans,10-trans-Geranylgeranyl diphosphate6699-20-3
Average450.4432Da
Monoisotopic450.19362653Da

Displaying 1–6 of 6 metabolites

Health Effects

Health ConditionRelationReference
Food poisoningCausesPMC1524862
Gas gangreneCausesPMC1524862
Clostridial myonecrosisCausesPMC1524862
Enteritis necroticansCausesPMC1524862
Non-foodborne gastrointestinal infectionsCausesPMC1524862
Gas gangreneCausesPMC5113727
BacteremiasCausesPMC5113727
Wound infectionCausesPMC5113727

Displaying health effects 51 – 58 of 58 in total