Clostridioides difficile str. RA09_70

Gram-positiveRodMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Peptostreptococcales

Family

Peptostreptococcaceae

Genus

Clostridioides

Description

Clostridioides difficile strain RA09_70 is a Gram-positive, rod-shaped bacterium that typically organizes itself in chains, pairs, or as single cells. This anaerobic organism thrives optimally at a temperature of 37.0 °C, which aligns with the physiological conditions of its host-associated habitat. As a chemoorganotroph, C. difficile strain RA09_70 derives its energy from organic compounds, reinforcing its adaptation to environments rich in host-derived nutrients. The specific arrangement of cells in chains and pairs suggests a potential for communication or cooperative behavior, characteristics that may play a role in its survival and persistence within host environments. The strain's anaerobic nature indicates it occupies ecological niches that are devoid of oxygen, further emphasizing its specialized adaptations to the gut microbiota of mammals, where it predominantly resides. This combination of traits underscores the bacterium's ability to thrive in the complex and competitive ecosystem of the gastrointestinal tract, where it may interact with other microbial inhabitants and host factors. Understanding these characteristics can provide valuable insights into the ecological dynamics of gut microbiomes and the potential roles of C. difficile in various host-associated processes.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderPeptostreptococcales
FamilyPeptostreptococcaceae
GenusClostridioides
SpeciesClostridioides difficile
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes1
Image of Clostridioides difficile str. RA09_70
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Not Available
Cell arrangementChains - Pairs - Singles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Clostridioides difficile str. RA09_70

Accession NumberJPPA00000000.1

Gene Summary

Adenine Count

1519866 bp

Thymine Count

1506247 bp

Guanine Count

608909 bp

Cytosine Count

597184 bp

Genome Length

4232226 bp

Protein-coding Genes

3643 genes

Non-Coding Genes

111 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
Putative tail sheath proteinIM33_05125Not Available+1044252 - 104556248743.5
Putative core tailIM33_05130P54332+1045581 - 104605117817.9
Conserved hypothetical protein (xkdn-like)IM33_05135Not Available+1046120 - 104656016445.3
copg family transcriptional regulatorIM33_05155Not Available+1048843 - 10490196765.24
Bro-n domain-containing proteinIM33_05160Not Available+1049145 - 104995130653.5
hypothetical proteinIM33_05165Not Available+1050011 - 10501967611.35
cro/cl family transcriptional regulatorIM33_05170Not Available-1050640 - 10508437702.47
Bro-n domain-containing proteinIM33_05175Not Available+1051435 - 105186616617.2
LipoproteinIM33_05185Not Available+1052639 - 105319921074.1
Hypothetical proteinIM33_05190Not Available+1053264 - 105381220165.7

Displaying genes 11 – 20 of 3754 in total

Pathways

1 pathway

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

182 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000232(4S)-perillyl alcoholC10H16OChemical structure of (4S)-perillyl alcoholNot available
Average152.237Da
Monoisotopic152.1201151Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm0000272(E)-4-coumarateC9H7O3Chemical structure of (E)-4-coumarateNot available
Average163.1501Da
Monoisotopic163.0395191Da
BASm0000277keto-L-sorboseC6H12O6Chemical structure of keto-L-sorboseNot available
Average180.1559Da
Monoisotopic180.0633881Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da

Displaying 1–10 of 182 metabolites