Clostridium butyricum

Gram-positiveMotileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Clostridiaceae

Genus

Clostridium

Description

Clostridium butyricum is a Gram-positive, rod-shaped microbe that thrives in a mesophilic temperature range, preferring temperatures between 25-40°C. It is classified as a chemoheterotroph, utilizing organic compounds as its energy source. C. butyricum produces energy through anaerobic fermentation, specifically by converting glucose into butyric acid, acetate, and hydrogen gas. This process is essential for its survival, as it allows the microbe to survive in environments where oxygen is scarce or absent. The Gram-staining property of C. butyricum indicates that its cell wall contains a thick peptidoglycan layer, which is characteristic of Gram-positive bacteria. Its rod-shaped morphology allows it to move efficiently through its surroundings, facilitating the absorption of nutrients and the release of waste products. C. butyricum is an obligate anaerobe, meaning it cannot survive in the presence of oxygen and will die if exposed to it. This adaptation is crucial for its survival in environments where oxygen levels are low, such as the human gut. Its anaerobic metabolism also enables it to produce short-chain fatty acids, which can serve as energy sources for other microorganisms. This microbe can be found in various body sites, including the human gut, where it plays a role in the decomposition of complex nutrients and the production of volatile fatty acids. C. butyricum has also been isolated from soil, freshwater, and marine environments, highlighting its remarkable adaptability. In addition to its role in decomposition and nutrient cycling, C. butyricum has been explored for its potential applications in medicine and biotechnology. For instance, its ability to produce butyric acid has been exploited in the development of probiotics, which can help maintain a healthy gut microbiome. Furthermore, its enzymes have been used in the production of biofuels and bioplastics, demonstrating its significance in the search for sustainable energy solutions.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyClostridiaceae
GenusClostridium
SpeciesClostridium butyricum
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeNot Available
MobilityYes
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperatureNot Available
Temperature rangemesophilic
Habitatrumen
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Sus scrofa
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Clostridium butyricum strain UBCB 70 Scaffold81, whole genome

Gene Summary

Adenine Count

1629875 bp

Thymine Count

1627298 bp

Guanine Count

655174 bp

Cytosine Count

655185 bp

Genome Length

4578933 bp

Protein-coding Genes

3843 genes

Non-Coding Genes

218 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
dhh family phosphoesteraseEI970_01295Not AvailableNegative264934 - 26687172453.4
mazg-like family proteinEI970_01300Not AvailableNegative266892 - 26721512167.1
30s ribosomal protein s18EI970_01305Not AvailableNegative267495 - 26775210026.3
single-stranded dna-binding proteinEI970_01310Not AvailableNegative267781 - 26823316055.6
30s ribosomal protein s6EI970_01315Not AvailableNegative268247 - 26853410942.1
duf951 domain-containing proteinEI970_01320Not AvailableNegative268636 - 2688307197.08
mechanosensitive ion channel family proteinEI970_01325Not AvailableNegative268830 - 26973233137.4
duf3343 domain-containing proteinEI970_01330Not AvailableNegative269756 - 2699959360.37
lysine transporter lyseEI970_01335Not AvailablePositive270148 - 27079524095.2
aminotransferase class v-fold plp-dependent enzymeEI970_01340Not AvailablePositive270849 - 27200041853.0

Displaying genes 381 – 390 of 4061 in total

Metabolites

142 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000719chloramphenicol 3-acetateC13H14Cl2N2O6Chemical structure of chloramphenicol 3-acetateNot available
Average365.16Da
Monoisotopic364.0228916Da
BASm0005410heptadecanoyl-CoAC38H64N7O17P3SChemical structure of heptadecanoyl-CoANot available
Average1015.95Da
Monoisotopic1015.331420116Da
BASm00055071-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateC35H67O8PChemical structure of 1-tetradecanoyl-2-(9Z)-octadecenoyl-sn-glycero-3-phosphateNot available
Average646.887Da
Monoisotopic646.4573561Da
BASm0014067p-Aminobenzoic acidC7H7NO2Chemical structure of p-Aminobenzoic acid150-13-0
Average137.136Da
Monoisotopic137.047678473Da
BASm0014072PectinC6H10O7Chemical structure of Pectin9000-69-5
Average194.1394Da
Monoisotopic194.042652674Da
BASm0014084GlycogenC24H42O21Chemical structure of Glycogen9005-79-2
Average666.5777Da
Monoisotopic666.221858406Da
BASm0014085AmylopectinC30H52O26Chemical structure of Amylopectin9037-22-3
Average828.7183Da
Monoisotopic828.274681836Da
BASm0014086Amylose(C12H20O11)nC2H6Chemical structure of Amylose9005-82-7Not available
BASm0017267PS(16:0/16:0)C38H74NO10PChemical structure of PS(16:0/16:0)3036-82-6
Average735.981Da
Monoisotopic735.505034585Da
BASm0017269PA(16:0/16:0)C35H69O8PChemical structure of PA(16:0/16:0)7091-44-3
Average648.903Da
Monoisotopic648.47300618Da

Displaying 1–10 of 142 metabolites

Health Effects

No health effects information available for this bacterium.