Geobacillus stearothermophilus

RodAerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Caryophanales

Family

Anoxybacillaceae

Genus

Geobacillus

Description

Geobacillus stearothermophilus is a gram-positive, rod-shaped bacterium classified as a thermophile, thriving optimally at elevated temperatures, typically around 55-75°C. This microbe is a chemoheterotroph, obtaining its energy through the decomposition of organic compounds, and it is an obligate aerobe, requiring oxygen for its growth and metabolism.As a member of the Bacillaceae family, G. stearothermophilus showcases characteristic resilience; it forms durable endospores that allow it to survive extreme conditions, including high heat and desiccation. These spores can withstand autoclaving, a feature that makes this organism particularly significant in sterilization validation processes in laboratories and healthcare settings. The ability to thrive in such harsh environments also points to its widespread presence in soil and thermal springs, where it plays a crucial role in the decomposition of organic matter. In laboratory and industrial applications, G. stearothermophilus is often used as a biological indicator to assess the effectiveness of sterilization processes, particularly in the medical field. Its spores serve as a benchmark; if the spores are killed during sterilization, it provides confidence that other pathogens have also been eliminated.Furthermore, G. stearothermophilus is notable for producing thermostable enzymes, which are utilized in various biotechnological applications, such as biofuel production and food processing, due to their activity at high temperatures. This bacterium’s ability to thrive under extreme conditions and its practical applications in industry highlight its significance within the microbial world.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderCaryophanales
FamilyAnoxybacillaceae
GenusGeobacillus
SpeciesGeobacillus stearothermophilus
StrainNo strain

Profile

Physiology
Gram staining propertiesVariable
ShapeRod
MobilityNot Available
Flagellar presenceNot Available
Number of membranesNot Available
Ecology, Host, and Life Cycle
Oxygen requirementsAerobe
Optimal temperatureNot Available
Temperature rangethermophilic
Habitatactive volcanic area; spoiled canned food
Biotic relationshipNot Available
Host(s)Not Available
Cell arrangementNot Available
SporulationNot Available
Energy sourceNot Available
PathogenicityNot Available

Genome Summary

Geobacillus stearothermophilus

Accession NumberLQYV00000000.1

Gene Summary

Adenine Count

661375 bp

Thymine Count

656554 bp

Guanine Count

729215 bp

Cytosine Count

725845 bp

Genome Length

2777152 bp

Protein-coding Genes

3109 genes

Non-Coding Genes

152 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProtStrandCoordinatesMolecular Weight
cyclic di-gmp phosphodiesterase response regulator rpfgAVP43_00023Q9KL18+7569 - 871442869.9
5s ribosomal rnaNot AvailableNot Available+8285 - 8396Not Available
cystathionine beta-lyase metcAVP43_00024O31632-8753 - 993143170.7
5s ribosomal rnaNot AvailableNot Available+10222 - 10333Not Available
cystathionine gamma-synthase/o-acetylhomoserine (thiol)-lyaseAVP43_00025O31631-9935 - 1103840943.9
hypothetical proteinAVP43_00026O31630+11766 - 1249427462.9
putative phosphoesterase yjcgAVP43_00027Q5L1N1+12533 - 1305720421.3
putative n-acetyltransferase yjcfAVP43_00028O31628+13054 - 1348816044.2
5s ribosomal rnaNot AvailableNot Available+13558 - 13669Not Available
hypothetical proteinAVP43_00029O31625-13606 - 138639769.81

Displaying genes 31 – 40 of 6618 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

170 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00007164-methylsulfanyl-2-oxobutanoateC5H7O3SChemical structure of 4-methylsulfanyl-2-oxobutanoateNot available
Average147.17Da
Monoisotopic147.012138839Da
BASm0000848hexanoateC6H11O2Chemical structure of hexanoateNot available
Average115.1503Da
Monoisotopic115.075904596Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da
BASm0000976enol-oxaloacetateC4H2O5Chemical structure of enol-oxaloacetateNot available
Average130.056Da
Monoisotopic129.9913203Da

Displaying 1–10 of 170 metabolites