Streptococcus intermedius

Gram-positiveCocciFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus intermedius is a Gram-positive coccus that typically arranges itself in pairs or chains. This microbe is a facultative anaerobe, capable of surviving in both aerobic and anaerobic environments, which allows it to thrive in diverse habitats, including brain abscesses, dental plaques, and various regions of the oral cavity. S. intermedius possesses true flagella, a trait that may contribute to its motility within these niches. This bacterium is known to exhibit pathogenicity in animals, indicating its potential role in various infectious processes. The organism has a single replicon and is represented by the genome accession RJOK00000000.1, which provides a basis for genomic studies and further understanding of its biological functions. Interestingly, the presence of S. intermedius in dental plaques highlights its possible involvement in oral health and disease, suggesting a dual role in both commensal and pathogenic interactions within the oral microbiome. This adaptability and association with specific habitats underscore the complex nature of its ecological interactions.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus intermedius
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNot Available
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus intermedius
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeNot Available
Habitatbrain abscesses; dental plaques; mouth; oral cavity
Biotic relationshipNot Available
Host(s)Homo sapiens, Oryctolagus cuniculus
Cell arrangementPairs, Chains
SporulationNot Available
Energy sourceNot Available
PathogenicityAnimal

Genome Summary

Streptococcus intermedius strain A4 D8831_contig026, whole genome

Gene Summary

Adenine Count

626453 bp

Thymine Count

618465 bp

Guanine Count

395821 bp

Cytosine Count

352484 bp

Genome Length

1995143 bp

Protein-coding Genes

1891 genes

Non-Coding Genes

95 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinD8831_05215Not AvailablePositive1066083 - 10662235109.13
Gp9D8831_05220Not AvailablePositive1066327 - 10665247334.8
Hypothetical proteinD8831_05225Not AvailablePositive1066533 - 106689513774.6
Hypothetical proteinD8831_05230Not AvailablePositive1066917 - 106720111247.5
hypothetical proteinD8831_05235Not AvailablePositive1067205 - 10674298782.62
Hypothetical proteinD8831_05240Not AvailablePositive1067431 - 106818929607.2
Hypothetical proteinD8831_05245Not AvailablePositive1068189 - 10683807204.55
Yopx domain proteinD8831_05250Not AvailablePositive1068377 - 106878715600.1
hypothetical proteinD8831_05255Not AvailablePositive1068784 - 106909211967.6
hypothetical proteinD8831_05260Not AvailablePositive1069181 - 106943510272.1

Displaying genes 11 – 20 of 1986 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

172 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001167triphosphateO10P3Chemical structure of triphosphate14127-68-5
Average252.9153Da
Monoisotopic252.8704308Da
BASm0001639CobinamideC48H72CoN11O8Chemical structure of Cobinamide13497-85-3
Average990.0874Da
Monoisotopic989.4897335Da
BASm0001661Cu(2+)CuChemical structure of Cu(2+)7440-50-8
Average63.546Da
Monoisotopic62.929601079Da
BASm00022412-demethylmenaquinone-8C50H70O2Chemical structure of 2-demethylmenaquinone-8Not available
Average703.0896Da
Monoisotopic702.5375815Da
BASm0002780orotidine 5'-phosphateC10H10N2O11PNot available2149-82-8
Average365.168Da
Monoisotopic365.003866888Da
BASm0002909O-acetyl-L-homoserineC6H11NO4Chemical structure of O-acetyl-L-homoserine7540-67-2
Average161.1558Da
Monoisotopic161.0688078Da

Displaying 1–10 of 172 metabolites

Health Effects

Health ConditionRelationReference
PeriodontitisCausesPMC11792871
Pyogenic infection of the central nervous system, pleural space or liverCausesPMC11792871
Intracranial suppurationCausesPMC11792871
BacteraemiaCausesPMC11792871
IcsCausesPMC11792871
Invasive infectionCausesPMC11792871
Brain abscessesCausesPMC11792871
Deep infectionsCausesPMC1435756
Deep neck infectionsCausesPMC1435756
Cervical lymphadenitisCausesPMC1435756

Displaying health effects 1 – 10 of 27 in total