Streptococcus pyogenes

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pyogenes is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. This non-motile organism lacks flagella and is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. Its optimal growth temperature is around 30°C, placing it within the mesophilic temperature classification. As a host-associated microbe, S. pyogenes is primarily found in human environments and is recognized for its pathogenicity, contributing to a range of human diseases. The bacterium has a single cellular membrane and contains 13 replicons, which are critical for its genetic diversity and adaptability. The genome of S. pyogenes is represented by multiple accessions, indicating a complex genetic structure that may support its survival and pathogenic potential. S. pyogenes also exhibits a free-living biotic relationship, suggesting that while it is primarily associated with human hosts, it may also exist in other ecological niches. This dual lifestyle could facilitate its transmission and persistence in various environments, highlighting a significant aspect of its ecology and potential impact on public health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pyogenes
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pyogenes
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1617 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

13

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
cysteine synthase aE6A91_01885Not AvailablePositive371882 - 37282333242.3
s1 rna-binding domain-containing proteinE6A91_01890Not AvailableNegative372841 - 37321814343.3
bifunctional cof-type had-iib family hydrolase/peptidylprolyl isomeraseE6A91_01895Not AvailableNegative373218 - 37461851690.7
response regulator transcription factorE6A91_01900Not AvailableNegative374655 - 37529623694.8
sensor histidine kinaseE6A91_01905Not AvailableNegative375289 - 37629338557.0
transporterE6A91_01910Not AvailableNegative376290 - 37703328693.5
stk1 family pasta domain-containing ser/thr kinaseE6A91_01915Not AvailableNegative377105 - 37900368864.0
stp1/irep family pp2c-type ser/thr phosphataseE6A91_01920Not AvailableNegative379000 - 37974027021.8
16s rrna (cytosine(967)-c(5))-methyltransferase rsmbE6A91_01925Not AvailableNegative379778 - 38110049615.4
methionyl-trna formyltransferaseE6A91_01930Not AvailableNegative381090 - 38202533672.3

Displaying genes 491 – 500 of 21613 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionCausesPMC11555966
Suppurative pharyngitisCausesPMC11555966
TonsillitisCausesPMC11555966
ScarlatinaCausesPMC11555966
Brain abscessCausesPMC11555966
Sterile-site infectionsCausesPMC11555966
Streptococcal toxic shock syndrome (stss)CausesPMC11735781
Necrotizing fasciitisCausesPMC11735781
MeningitisCausesPMC11735781
Acute rheumatic fever (arf)CausesPMC11735781

Displaying health effects 1 – 10 of 62 in total