Streptococcus pyogenes

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus pyogenes is a Gram-positive bacterium characterized by its cocci shape and arrangement in chains or pairs. This non-motile organism lacks flagella and is classified as a facultative anaerobe, allowing it to thrive in varying oxygen conditions. Its optimal growth temperature is around 30°C, placing it within the mesophilic temperature classification. As a host-associated microbe, S. pyogenes is primarily found in human environments and is recognized for its pathogenicity, contributing to a range of human diseases. The bacterium has a single cellular membrane and contains 13 replicons, which are critical for its genetic diversity and adaptability. The genome of S. pyogenes is represented by multiple accessions, indicating a complex genetic structure that may support its survival and pathogenic potential. S. pyogenes also exhibits a free-living biotic relationship, suggesting that while it is primarily associated with human hosts, it may also exist in other ecological niches. This dual lifestyle could facilitate its transmission and persistence in various environments, highlighting a significant aspect of its ecology and potential impact on public health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus pyogenes
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranes1
Image of Streptococcus pyogenes
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature30
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa
Cell arrangementChains - Pairs
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Gene Summary

Adenine Count

Not Available

Thymine Count

Not Available

Guanine Count

Not Available

Cytosine Count

Not Available

Genome Length

Not Available

Protein-coding Genes

1617 genes

Non-Coding Genes

258 genes

# of Chromosomes/Plasmids

13

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
mfs transporterE6A91_00740Not AvailableNegative147098 - 14829143419.5
duf853 domain-containing proteinE6A91_00745Not AvailableNegative148413 - 14991554960.6
dephospho-coa kinaseE6A91_00750Not AvailableNegative150105 - 15069821968.7
dna-formamidopyrimidine glycosylaseE6A91_00755Not AvailableNegative150695 - 15152230703.9
rgg/gadr/mutr family transcriptional regulatorE6A91_00760Not AvailableNegative151694 - 15256033977.8
peptide pheromone shp2E6A91_00765Not AvailablePositive152649 - 1527172431.3
hypothetical proteinE6A91_00770Not AvailablePositive152867 - 1531098975.57
quorum-sensing system protein stcaE6A91_00775Not AvailablePositive153631 - 15390010050.7
histidine kinaseE6A91_00780Not AvailableNegative154248 - 15469416602.4
hypothetical proteinE6A91_00785Not AvailableNegative154739 - 15573436394.4

Displaying genes 271 – 280 of 21613 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Skin and soft tissue infectionCausesPMC11555966
Suppurative pharyngitisCausesPMC11555966
TonsillitisCausesPMC11555966
ScarlatinaCausesPMC11555966
Brain abscessCausesPMC11555966
Sterile-site infectionsCausesPMC11555966
Streptococcal toxic shock syndrome (stss)CausesPMC11735781
Necrotizing fasciitisCausesPMC11735781
MeningitisCausesPMC11735781
Acute rheumatic fever (arf)CausesPMC11735781

Displaying health effects 1 – 10 of 62 in total