Streptococcus salivarius

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus salivarius is a Gram-positive coccus that typically forms chains and pairs. This non-motile bacterium is classified as a facultative anaerobe and thrives in mesophilic temperature ranges, making it well-adapted to the human oral cavity and upper respiratory tract. It is a free-living microbe, commonly found in association with its host, suggesting a symbiotic relationship. S. salivarius is nonsporulating and possesses four replicons in its genome, which may contribute to its genetic diversity and adaptability. The strain is notable for its presence in the human microbiome, where it plays a role in maintaining oral health and potentially inhibiting pathogenic bacteria. While S. salivarius is primarily recognized for its commensal role, it is also associated with human pathogenicity under certain conditions. The genome accessions for this organism include PKHZ00000000.1, QRSW00000000.1, QRUM00000000.1, and RJNF00000000.1, indicating a well-characterized genetic framework that supports further research into its functions and implications in human health. Overall, S. salivarius exemplifies the complex dynamics of host-associated microbiota, balancing its beneficial activities with the potential for pathogenicity, reflecting the intricate relationships within the human microbiome.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus salivarius
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus salivarius
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus salivarius strain AF24-6AC AF24-6AC.Scaf31, whole

Gene Summary

Adenine Count

674854 bp

Thymine Count

671441 bp

Guanine Count

422854 bp

Cytosine Count

462925 bp

Genome Length

2232352 bp

Protein-coding Genes

1968 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
marr family transcriptional regulatorCYK23_07315Not AvailablePositive1476709 - 147717017669.7
eve domain-containing proteinCYK23_07320Not AvailablePositive1477163 - 147758816659.0
cpbp family intramembrane metalloproteaseCYK23_07325Not AvailableNegative1477702 - 147831622642.5
duf4037 domain-containing proteinCYK23_07335Not AvailablePositive1478815 - 147961231205.4
d-tyrosyl-trna(tyr) deacylaseCYK23_07340Not AvailableNegative1479705 - 148014816293.6
bifunctional (p)ppgpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolaseCYK23_07345Not AvailableNegative1480214 - 148243384362.6
hypothetical proteinCYK23_07350Not AvailableNegative1482565 - 148284910235.3
hypothetical proteinCYK23_07355Not AvailableNegative1482836 - 148324016554.2
duf2974 domain-containing proteinCYK23_07360Not AvailableNegative1483225 - 148458650847.1
duf1310 domain-containing proteinCYK23_07365Not AvailableNegative1484593 - 148498514776.3

Displaying genes 7831 – 7840 of 8810 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC11536889
BacteremiaCausesPMC11536889
EndocarditisCausesPMC11536889
MeningitisCausesPMC11536889
PeritonitisCausesPMC9615012

Displaying health effects 1 – 5 of 5 in total