Streptococcus salivarius

Gram-positiveCocciNon-motileFacultative anaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Bacilli

Order

Lactobacillales

Family

Streptococcaceae

Genus

Streptococcus

Description

Streptococcus salivarius is a Gram-positive coccus that typically forms chains and pairs. This non-motile bacterium is classified as a facultative anaerobe and thrives in mesophilic temperature ranges, making it well-adapted to the human oral cavity and upper respiratory tract. It is a free-living microbe, commonly found in association with its host, suggesting a symbiotic relationship. S. salivarius is nonsporulating and possesses four replicons in its genome, which may contribute to its genetic diversity and adaptability. The strain is notable for its presence in the human microbiome, where it plays a role in maintaining oral health and potentially inhibiting pathogenic bacteria. While S. salivarius is primarily recognized for its commensal role, it is also associated with human pathogenicity under certain conditions. The genome accessions for this organism include PKHZ00000000.1, QRSW00000000.1, QRUM00000000.1, and RJNF00000000.1, indicating a well-characterized genetic framework that supports further research into its functions and implications in human health. Overall, S. salivarius exemplifies the complex dynamics of host-associated microbiota, balancing its beneficial activities with the potential for pathogenicity, reflecting the intricate relationships within the human microbiome.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassBacilli
OrderLactobacillales
FamilyStreptococcaceae
GenusStreptococcus
SpeciesStreptococcus salivarius
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeCocci
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Streptococcus salivarius
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperatureNot Available
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens
Cell arrangementChains-Pairs
SporulationNonsporulating
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Streptococcus salivarius strain AF24-6AC AF24-6AC.Scaf31, whole

Gene Summary

Adenine Count

674854 bp

Thymine Count

671441 bp

Guanine Count

422854 bp

Cytosine Count

462925 bp

Genome Length

2232352 bp

Protein-coding Genes

1968 genes

Non-Coding Genes

57 genes

# of Chromosomes/Plasmids

4

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
zinc-ribbon domain-containing proteinCYK23_05490Not AvailablePositive1109959 - 11101959284.13
heme abc transporter atp-binding proteinCYK23_05495Not AvailableNegative1110250 - 111179158454.9
duf898 domain-containing proteinCYK23_05500Not AvailableNegative1111903 - 111221112016.9
5'-methylthioadenosine/s-adenosylhomocysteine nucleosidaseCYK23_05505Not AvailableNegative1112224 - 111291625009.4
hypothetical proteinCYK23_05510Not AvailableNegative1112993 - 111341516134.9
nudix hydrolaseCYK23_05515Not AvailableNegative1113428 - 111397920812.6
bifunctional udp-n-acetylglucosamine diphosphorylase/glucosamine-1-phosphate n-acetyltransferase glmuCYK23_05520Not AvailableNegative1113988 - 111536749633.9
hypothetical proteinCYK23_05525Not AvailableNegative1115495 - 111628930456.0
hypothetical proteinCYK23_05530Not AvailableNegative1116584 - 11167094634.6
padr family transcriptional regulatorCYK23_05535Not AvailableNegative1116693 - 111731923918.0

Displaying genes 7481 – 7490 of 8810 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
PneumoniaCausesPMC11536889
BacteremiaCausesPMC11536889
EndocarditisCausesPMC11536889
MeningitisCausesPMC11536889
PeritonitisCausesPMC9615012

Displaying health effects 1 – 5 of 5 in total