Faecalibacterium prausnitzii

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Oscillospiraceae

Genus

Faecalibacterium

Description

Faecalibacterium prausnitzii is a Gram-positive, non-motile rod-shaped bacterium that is classified as an anaerobe and a chemoheterotroph. This organism does not form spores and possesses true flagella, which may play a role in its motility under specific conditions, despite its overall non-motile classification. It thrives optimally at a temperature of 37.0°C, indicating its mesophilic nature, and it is found in diverse habitats. The genomic structure of Faecalibacterium prausnitzii is notable for containing five replicons, which may contribute to its genetic diversity and adaptability. The bacterium is significant in the context of human gut microbiota, where it plays a crucial role in maintaining intestinal health and homeostasis. The presence of Faecalibacterium prausnitzii in the gut has been associated with beneficial effects, such as anti-inflammatory properties, highlighting its importance in the study of gut microbiome dynamics. Understanding its traits can provide insights into its functional roles within microbial communities and its potential implications for human health.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyOscillospiraceae
GenusFaecalibacterium
SpeciesFaecalibacterium prausnitzii
StrainNo strain

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Faecalibacterium prausnitzii
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Faecalibacterium prausnitzii strain 2789STDY5834970 genome

Gene Summary

Adenine Count

678569 bp

Thymine Count

664153 bp

Guanine Count

860749 bp

Cytosine Count

848645 bp

Genome Length

3054197 bp

Protein-coding Genes

2784 genes

Non-Coding Genes

84 genes

# of Chromosomes/Plasmids

5

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
endonuclease iiiERS852582_00032P73715Negative33202 - 3389125266.9
replication-associated recombination protein aERS852582_00033O34528Positive34064 - 3533846433.5
peroxide operon regulatorERS852582_00034Not AvailablePositive35363 - 3576714979.9
(dimethylallyl)adenosine trna methylthiotransferase miabERS852582_00035Q8RA72Positive35885 - 3727651955.9
protein of uncharacterised function (duf964)ERS852582_00036Not AvailablePositive37338 - 3774514928.6
dna mismatch repair protein mutsERS852582_00037B8I2Q5Positive37858 - 4047396539.3
dna mismatch repair protein mutlERS852582_00038C4ZA52Positive40510 - 4264277399.6
trna dimethylallyltransferaseERS852582_00039O31795Positive42626 - 4357634707.4
hlyd family secretion proteinERS852582_00040Not AvailablePositive43582 - 4489546758.1
cell division protein sepfERS852582_00041A6TRY5Positive45005 - 4547217156.1

Displaying genes 61 – 70 of 13948 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

143 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000400(R)-10-hydroxyoctadecanoateC18H35O3Chemical structure of (R)-10-hydroxyoctadecanoateNot available
Average299.476Da
Monoisotopic299.2591686Da
BASm0000837dimethylmaleateC6H6O4Chemical structure of dimethylmaleateNot available
Average142.111Da
Monoisotopic142.027705833Da
BASm00008763-hydroxypyruvateC3H3O4Chemical structure of 3-hydroxypyruvateNot available
Average103.054Da
Monoisotopic103.003682157Da
BASm0000908propanoateC3H5O2Chemical structure of propanoateNot available
Average73.072Da
Monoisotopic73.029502981Da
BASm0000976enol-oxaloacetateC4H2O5Chemical structure of enol-oxaloacetateNot available
Average130.056Da
Monoisotopic129.9913203Da

Displaying 1–10 of 143 metabolites

Health Effects

No health effects information available for this bacterium.