Faecalibacterium prausnitzii str. CNCM I 4542

Gram-positiveRodNon-motileAnaerobe

Kingdom

Bacillati

Phylum

Bacillota

Class

Clostridia

Order

Eubacteriales

Family

Oscillospiraceae

Genus

Faecalibacterium

Description

Faecalibacterium prausnitzii str. CNCM I 4542 is a Gram-positive, rod-shaped bacterium that exhibits a nonsporulating phenotype and is classified as an anaerobic chemoheterotroph. This strain demonstrates optimal growth at 37.0°C, suggesting its adaptation to the warm environments typically encountered within the mammalian gastrointestinal tract. F. prausnitzii str. CNCM I 4542 is particularly noteworthy for its presence in diverse habitats, including the human gut, where it plays a significant role in maintaining intestinal health. As a member of the gut microbiota, it is involved in various metabolic processes, contributing to the fermentation of dietary fibers and the production of short-chain fatty acids, which are beneficial for colon health and have anti-inflammatory properties. This bacterium's ability to thrive in anaerobic conditions aligns with its ecological niche within the gastrointestinal tract, where oxygen levels are minimal. The metabolic activities of F. prausnitzii str. CNCM I 4542 not only support its survival but also influence the overall microbial composition and functionality in the gut ecosystem. Its presence is often associated with a healthy gut microbiome, making it a subject of interest in studies focused on gut health and microbiome-related diseases. The unique metabolic capabilities of this strain underscore its importance in the complex interactions within the gut microbiome, highlighting its potential role in promoting host health through microbial balance and metabolic support.

Taxonomy

KingdomBacillati
PhylumBacillota
ClassClostridia
OrderEubacteriales
FamilyOscillospiraceae
GenusFaecalibacterium
SpeciesFaecalibacterium prausnitzii
StrainCNCM I 4542

Profile

Physiology
Gram staining propertiesPositive
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Faecalibacterium prausnitzii str. CNCM I 4542
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipNot Available
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Faecalibacterium prausnitzii strain CNCM I 4542 Scaffold_105,

Gene Summary

Adenine Count

652509 bp

Thymine Count

634623 bp

Guanine Count

823819 bp

Cytosine Count

803243 bp

Genome Length

2914466 bp

Protein-coding Genes

2575 genes

Non-Coding Genes

270 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
penicillin-binding proteinCGS50_012765Not AvailablePositive2506494 - 250726428420.4
abc transporter permeaseCGS50_012770Not AvailableNegative2507449 - 2510724120135.0
abc transporter atp-binding proteinCGS50_012775Not AvailableNegative2510718 - 251142226023.0
transcriptional regulator, iclr family proteinCGS50_012780Not AvailableNegative2511595 - 251223022278.7
atp-dependent zinc metalloprotease ftshCGS50_012785Not AvailableNegative2512402 - 251424067248.0
2-isopropylmalate synthaseCGS50_012790Not AvailablePositive2514994 - 251664661113.6
3-isopropylmalate dehydratase large subunitCGS50_012795Not AvailablePositive2516679 - 251793844729.1
3-isopropylmalate dehydratase small subunitCGS50_012800Not AvailablePositive2517957 - 251844817704.2
3-isopropylmalate dehydrogenaseCGS50_012805Not AvailablePositive2518634 - 251970738923.9
uracil phosphoribosyltransferaseCGS50_012810Not AvailableNegative2519810 - 252043622778.1

Displaying genes 2471 – 2480 of 2845 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

No health effects information available for this bacterium.