Bacteroides fragilis

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis is a Gram-negative, rod-shaped bacterium characterized by its non-motile nature and arrangement as single cells. This organism thrives in anaerobic environments, demonstrating its adaptation as a chemoorganotroph that derives energy from organic compounds. Optimal growth occurs at 37°C, classifying it as mesophilic. B. fragilis possesses two cellular membranes, a trait typical of Gram-negative bacteria, and contains two replicons in its genome, accessible through the genome accessions QRZH00000000.1 and QRKP00000000.1. B. fragilis is primarily associated with host organisms, where it exists as a free-living microbe. It is known to have pathogenic potential in humans, although specific pathogenic mechanisms are not detailed within the provided traits. This bacterium plays a significant role in the human gut microbiota, contributing to various metabolic processes and maintaining gut health. Its ability to thrive in anaerobic conditions and its nutritional versatility underscore its ecological significance within host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain AM15-16 AM15-16.Scaf40, whole genome

Gene Summary

Adenine Count

1509830 bp

Thymine Count

1489963 bp

Guanine Count

1128886 bp

Cytosine Count

1163404 bp

Genome Length

5292183 bp

Protein-coding Genes

4501 genes

Non-Coding Genes

81 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinDWW08_04545Not AvailableNegative1056560 - 105691613280.8
hypothetical proteinDWW08_04550Not AvailablePositive1057199 - 10573666190.46
hypothetical proteinDWW08_04555Not AvailablePositive1057395 - 105812928465.8
Hnh endonucleaseDWW08_04560Not AvailableNegative1058185 - 105851412718.2
hypothetical proteinDWW08_04565Not AvailableNegative1058675 - 105894410114.3
hypothetical proteinDWW08_04570Not AvailableNegative1058937 - 10591347790.22
3_nc_021794: hypothetical proteinDWW08_04575Not AvailableNegative1059159 - 10593597586.15
AttrNot AvailableNot AvailablePositive1069391 - 1069436Not Available
5s ribosomal rnaNot AvailableNot AvailablePositive3 - 113Not Available
dna-binding proteinDWW08_00005Not AvailablePositive101 - 38811381.7

Displaying genes 4671 – 4680 of 9069 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total