Bacteroides fragilis

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis is a Gram-negative, rod-shaped bacterium characterized by its non-motile nature and arrangement as single cells. This organism thrives in anaerobic environments, demonstrating its adaptation as a chemoorganotroph that derives energy from organic compounds. Optimal growth occurs at 37°C, classifying it as mesophilic. B. fragilis possesses two cellular membranes, a trait typical of Gram-negative bacteria, and contains two replicons in its genome, accessible through the genome accessions QRZH00000000.1 and QRKP00000000.1. B. fragilis is primarily associated with host organisms, where it exists as a free-living microbe. It is known to have pathogenic potential in humans, although specific pathogenic mechanisms are not detailed within the provided traits. This bacterium plays a significant role in the human gut microbiota, contributing to various metabolic processes and maintaining gut health. Its ability to thrive in anaerobic conditions and its nutritional versatility underscore its ecological significance within host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain AM15-16 AM15-16.Scaf40, whole genome

Gene Summary

Adenine Count

1509830 bp

Thymine Count

1489963 bp

Guanine Count

1128886 bp

Cytosine Count

1163404 bp

Genome Length

5292183 bp

Protein-coding Genes

4501 genes

Non-Coding Genes

81 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
l-serine ammonia-lyaseDW170_17725Not AvailablePositive3938018 - 393922643617.2
ribosome biogenesis proteinDW170_17730Not AvailableNegative3939330 - 393983018653.8
hypothetical proteinDW170_17735Not AvailableNegative3939868 - 394031116857.4
duf4738 domain-containing proteinDW170_17740Not AvailableNegative3940429 - 394098320723.0
duf4890 domain-containing proteinDW170_17745Not AvailableNegative3941133 - 394160017974.1
hypothetical proteinDW170_17750Not AvailablePositive3941993 - 394228611344.7
hypothetical proteinDW170_17755Not AvailablePositive3942261 - 394251210030.1
peroxiredoxinDW170_17760Not AvailablePositive3942538 - 394310421062.1
alkyl hydroperoxide reductase subunit fDW170_17765Not AvailablePositive3943205 - 394475555284.3
endonuclease/exonuclease/phosphatase family proteinDW170_17770Not AvailableNegative3944905 - 394593038873.3

Displaying genes 3421 – 3430 of 9069 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total