Bacteroides fragilis

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis is a Gram-negative, rod-shaped bacterium characterized by its non-motile nature and arrangement as single cells. This organism thrives in anaerobic environments, demonstrating its adaptation as a chemoorganotroph that derives energy from organic compounds. Optimal growth occurs at 37°C, classifying it as mesophilic. B. fragilis possesses two cellular membranes, a trait typical of Gram-negative bacteria, and contains two replicons in its genome, accessible through the genome accessions QRZH00000000.1 and QRKP00000000.1. B. fragilis is primarily associated with host organisms, where it exists as a free-living microbe. It is known to have pathogenic potential in humans, although specific pathogenic mechanisms are not detailed within the provided traits. This bacterium plays a significant role in the human gut microbiota, contributing to various metabolic processes and maintaining gut health. Its ability to thrive in anaerobic conditions and its nutritional versatility underscore its ecological significance within host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain AM15-16 AM15-16.Scaf40, whole genome

Gene Summary

Adenine Count

1509830 bp

Thymine Count

1489963 bp

Guanine Count

1128886 bp

Cytosine Count

1163404 bp

Genome Length

5292183 bp

Protein-coding Genes

4501 genes

Non-Coding Genes

81 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
duf4133 domain-containing proteinDW170_08330Not AvailablePositive1806499 - 180683112692.9
trag family conjugative transposon atpaseDW170_08335Not AvailablePositive1806828 - 180933296253.5
duf3876 domain-containing proteinDW170_08340Not AvailablePositive1809367 - 180974714394.4
duf4141 domain-containing proteinDW170_08345Not AvailablePositive1809771 - 181040024175.4
conjugative transposon protein trajDW170_08350Not AvailablePositive1810405 - 181140937104.7
conjugative transposon protein trakDW170_08355Not AvailablePositive1811441 - 181206424066.8
duf3989 domain-containing proteinDW170_08360Not AvailablePositive1812104 - 181239110890.2
conjugative transposon protein tramDW170_08365Not AvailablePositive1812372 - 181371848726.7
conjugative transposon protein tranDW170_08370Not AvailablePositive1813766 - 181475237177.9
conjugal transfer protein traoDW170_08375Not AvailablePositive1814755 - 181533021062.3

Displaying genes 1611 – 1620 of 9069 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total