Bacteroides fragilis

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis is a Gram-negative, rod-shaped bacterium characterized by its non-motile nature and arrangement as single cells. This organism thrives in anaerobic environments, demonstrating its adaptation as a chemoorganotroph that derives energy from organic compounds. Optimal growth occurs at 37°C, classifying it as mesophilic. B. fragilis possesses two cellular membranes, a trait typical of Gram-negative bacteria, and contains two replicons in its genome, accessible through the genome accessions QRZH00000000.1 and QRKP00000000.1. B. fragilis is primarily associated with host organisms, where it exists as a free-living microbe. It is known to have pathogenic potential in humans, although specific pathogenic mechanisms are not detailed within the provided traits. This bacterium plays a significant role in the human gut microbiota, contributing to various metabolic processes and maintaining gut health. Its ability to thrive in anaerobic conditions and its nutritional versatility underscore its ecological significance within host-associated environments.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain AM15-16 AM15-16.Scaf40, whole genome

Gene Summary

Adenine Count

1509830 bp

Thymine Count

1489963 bp

Guanine Count

1128886 bp

Cytosine Count

1163404 bp

Genome Length

5292183 bp

Protein-coding Genes

4501 genes

Non-Coding Genes

81 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
virulence protein eDW170_07720Not AvailableNegative1674522 - 167668183053.5
hypothetical proteinDW170_07725Not AvailableNegative1676747 - 167712714870.1
capsular polysaccharide transcription antiterminator uphyDW170_07735Not AvailablePositive1677872 - 167841120819.5
transcriptional regulatorDW170_07740Not AvailablePositive1678456 - 167894118402.4
undecaprenyl/decaprenyl-phosphate alpha-n-acetylglucosaminyl 1-phosphate transferaseDW170_07745Not AvailablePositive1678993 - 168009040852.5
lipopolysaccharide biosynthesis protein rfbhDW170_07750Not AvailablePositive1680109 - 168145250128.6
glucose-1-phosphate cytidylyltransferaseDW170_07755Not AvailablePositive1681490 - 168226629324.9
cdp-glucose 4,6-dehydrataseDW170_07760Not AvailablePositive1682272 - 168335140740.6
sdr family oxidoreductaseDW170_07765Not AvailablePositive1683353 - 168425234076.6
nad-dependent epimerase/dehydratase family proteinDW170_07770Not AvailablePositive1684255 - 168526838539.5

Displaying genes 1491 – 1500 of 9069 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total