Bacteroides fragilis str. DCMOUH0042B

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis str. DCMOUH0042B is a Gram-negative, rod-shaped bacterium that exists primarily as single cells and is classified as an anaerobe. This strain thrives optimally at a temperature of 37.0°C, aligning with the physiological conditions commonly found in the human body, which is its natural habitat. As a chemoorganotroph, Bacteroides fragilis str. DCMOUH0042B metabolizes organic compounds to derive energy, playing a crucial role in the degradation of complex carbohydrates within the host-associated environment. The presence of Bacteroides fragilis species in the gut microbiota is essential for maintaining intestinal health, particularly in the degradation of dietary fibers and other organic materials that are not readily digestible by the host. This metabolic capability may contribute to the overall balance of microbial communities in the gastrointestinal tract, influencing nutrient absorption and host metabolism. Furthermore, the unique anaerobic nature of this strain suggests adaptations that allow it to thrive in low-oxygen environments, which is characteristic of the gut ecosystem. Understanding the specific roles and interactions of Bacteroides fragilis str. DCMOUH0042B within its ecological niche could provide insights into its contributions to host health and the potential impacts of dysbiosis in gut microbiota.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainDCMOUH0042B

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis str. DCMOUH0042B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain DCMOUH0042B chromosome, complete

Gene Summary

Adenine Count

1453684 bp

Thymine Count

1458792 bp

Guanine Count

1112819 bp

Cytosine Count

1115962 bp

Genome Length

5141257 bp

Protein-coding Genes

4090 genes

Non-Coding Genes

93 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
sensor histidine kinaseHR50_RS00215Not AvailablePositive47902 - 4896341318.5
lytr/algr family response regulator transcription factorHR50_RS00220Not AvailablePositive48960 - 4973929745.0
4fe-4s dicluster domain-containing proteinHR50_RS00225Not AvailablePositive49828 - 5129754425.8
[fefe] hydrogenase h-cluster radical sam maturase hydeHR50_RS00230Not AvailablePositive51278 - 5231539785.9
[fefe] hydrogenase h-cluster radical sam maturase hydgHR50_RS00235Not AvailablePositive52328 - 5374653615.1
[fefe] hydrogenase h-cluster maturation gtpase hydfHR50_RS00240Not AvailablePositive53743 - 5491843578.8
6-bladed beta-propellerHR50_RS00245Not AvailableNegative55039 - 5623544267.9
beta-galactosidaseHR50_RS00250Not AvailableNegative56655 - 5896487928.4
phosphoglucosamine mutaseHR50_RS00255Not AvailableNegative59209 - 6059750228.5
duf4827 domain-containing proteinHR50_RS00260Not AvailableNegative60634 - 6127824512.0

Displaying genes 41 – 50 of 4189 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total