Bacteroides fragilis str. DCMOUH0042B

Gram-negativeRodNon-motileAnaerobe

Kingdom

Pseudomonadati

Phylum

Bacteroidota

Class

Bacteroidia

Order

Bacteroidales

Family

Bacteroidaceae

Genus

Bacteroides

Description

Bacteroides fragilis str. DCMOUH0042B is a Gram-negative, rod-shaped bacterium that exists primarily as single cells and is classified as an anaerobe. This strain thrives optimally at a temperature of 37.0°C, aligning with the physiological conditions commonly found in the human body, which is its natural habitat. As a chemoorganotroph, Bacteroides fragilis str. DCMOUH0042B metabolizes organic compounds to derive energy, playing a crucial role in the degradation of complex carbohydrates within the host-associated environment. The presence of Bacteroides fragilis species in the gut microbiota is essential for maintaining intestinal health, particularly in the degradation of dietary fibers and other organic materials that are not readily digestible by the host. This metabolic capability may contribute to the overall balance of microbial communities in the gastrointestinal tract, influencing nutrient absorption and host metabolism. Furthermore, the unique anaerobic nature of this strain suggests adaptations that allow it to thrive in low-oxygen environments, which is characteristic of the gut ecosystem. Understanding the specific roles and interactions of Bacteroides fragilis str. DCMOUH0042B within its ecological niche could provide insights into its contributions to host health and the potential impacts of dysbiosis in gut microbiota.

Taxonomy

KingdomPseudomonadati
PhylumBacteroidota
ClassBacteroidia
OrderBacteroidales
FamilyBacteroidaceae
GenusBacteroides
SpeciesBacteroides fragilis
StrainDCMOUH0042B

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Bacteroides fragilis str. DCMOUH0042B
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsAnaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementSingles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityHuman

Genome Summary

Bacteroides fragilis strain DCMOUH0042B chromosome, complete

Gene Summary

Adenine Count

1453684 bp

Thymine Count

1458792 bp

Guanine Count

1112819 bp

Cytosine Count

1115962 bp

Genome Length

5141257 bp

Protein-coding Genes

4090 genes

Non-Coding Genes

93 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
hypothetical proteinHR50_RS11145Not AvailablePositive2585061 - 258629647938.3
degt/dnrj/eryc1/strs family aminotransferaseHR50_RS11150Not AvailablePositive2586293 - 258740241196.6
glucose-1-phosphate cytidylyltransferaseHR50_RS11155Not AvailablePositive2587407 - 258817429371.3
cdp-glucose 4,6-dehydrataseHR50_RS11160Not AvailablePositive2588182 - 258927341710.8
dtdp-4-dehydrorhamnose 3,5-epimerase family proteinHR50_RS11165Not AvailablePositive2589261 - 258972217728.5
glycosyltransferase family 2 proteinHR50_RS11170Not AvailablePositive2589724 - 259064135968.0
o-antigen polymeraseHR50_RS11175Not AvailablePositive2590643 - 259181245344.6
polysaccharide biosynthesis proteinHR50_RS11180Not AvailablePositive2591821 - 259284338413.5
non-hydrolyzing udp-n-acetylglucosamine 2-epimeraseHR50_RS11185Not AvailablePositive2592831 - 259396143085.9
dtdp-4-dehydrorhamnose reductase family proteinHR50_RS11190Not AvailablePositive2593981 - 259483832028.3

Displaying genes 2051 – 2060 of 4189 in total

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
Ad pathologiesCausesPMC10482867
DiarrheaCausesPMC13367044
ColitisCausesPMC13367044
Tumor formationCausesPMC13367044
Anaerobic bacteremiaCausesPMC5704556
Intraabdominal abscessesCausesPMC5704556
Colorectal cancerCausesPMC11704243
CrcCausesPMC11704243
BacteremiaCausesPMC8554563
SepticemiaCausesPMC8554563

Displaying health effects 1 – 10 of 19 in total