Aggregatibacter actinomycetemcomitans str. 624

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Pasteurellales

Family

Pasteurellaceae

Genus

Aggregatibacter

Description

Aggregatibacter actinomycetemcomitans str. 624 is a Gram-negative, rod-shaped bacterium that exhibits facultative anaerobic growth, thriving optimally at 37.0°C. As a nonsporulating organism, it relies on a stable environment for survival and reproduction. This strain is classified as a chemoheterotroph, indicating that it derives its energy from organic compounds, which is consistent with its habitat within the host gut. The presence of A. actinomycetemcomitans in the gut suggests a potential role in the complex microbial communities that inhabit this environment. The bacterium’s ability to adapt to both aerobic and anaerobic conditions allows it to occupy diverse niches within the gut microbiome, where it may contribute to metabolic processes and nutrient cycling. While the specific ecological functions of this strain remain to be fully elucidated, its versatility in oxygen utilization and dependency on organic substrates underscore its potential importance in gut health and microbial interactions. Further research could illuminate its role in maintaining gut homeostasis or its interactions with other microbial species in the host.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderPasteurellales
FamilyPasteurellaceae
GenusAggregatibacter
SpeciesAggregatibacter actinomycetemcomitans
Strain624

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranesNot Available
Image of Aggregatibacter actinomycetemcomitans str. 624
AI-generated image based on bacteria physiology
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHost gut
Biotic relationshipNot Available
Host(s)Homo sapiens
Cell arrangementNot Available
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityNot Available

Genome Summary

Aggregatibacter actinomycetemcomitans strain 624 chromosome,

Gene Summary

Adenine Count

664143 bp

Thymine Count

656505 bp

Guanine Count

520280 bp

Cytosine Count

526980 bp

Genome Length

2367908 bp

Protein-coding Genes

2214 genes

Non-Coding Genes

145 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
is3 family transposaseACT75_RS07195P16940Negative1473364 - 147422733292.3
is3 family transposaseACT75_RS11965Not AvailableNegative1474406 - 14745073903.78
hypothetical proteinACT75_RS13115Not AvailableNegative1474570 - 147627963091.7
bifunctional glutamate--cysteine ligase gsha/glutathione synthetase gshbACT75_RS07210Q65RX0Negative1476286 - 147855985033.0
phosphoethanolamine transferaseACT75_RS07215P44974Positive1478791 - 148039260872.1
atp-dependent clp endopeptidase proteolytic subunit clppACT75_RS07220Q65RF6Positive1480636 - 148121721307.7
atp-dependent protease atp-binding subunit clpxACT75_RS07225P57981Positive1481227 - 148245945408.6
helix-turn-helix domain-containing proteinACT75_RS07230Not AvailableNegative1482522 - 148284511945.5
type ii toxin-antitoxin system rele/pare family toxinACT75_RS07235Not AvailableNegative1482838 - 148315211725.2
duf817 domain-containing proteinACT75_RS07240O34535Negative1483304 - 148414932773.7

Displaying genes 1551 – 1560 of 2359 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

117 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm0000377(S)-malateC4H4O5Chemical structure of (S)-malateNot available
Average132.0716Da
Monoisotopic132.005873238Da
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm0000401(S)-2-succinylamino-6-oxoheptanedioateC11H12NO8Chemical structure of (S)-2-succinylamino-6-oxoheptanedioateNot available
Average286.218Da
Monoisotopic286.0579371Da
BASm0000642S-adenosyl-4-methylsulfanyl-2-oxobutanoateC15H19N5O6SChemical structure of S-adenosyl-4-methylsulfanyl-2-oxobutanoateNot available
Average397.406Da
Monoisotopic397.105604055Da
BASm00006985-dehydro-2-deoxy-D-gluconateC6H9O6Chemical structure of 5-dehydro-2-deoxy-D-gluconateNot available
Average177.133Da
Monoisotopic177.04046159Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0001086scyllo-inososeC6H10O6Chemical structure of scyllo-inososeNot available
Average178.14Da
Monoisotopic178.0477381Da

Displaying 1–10 of 117 metabolites

Health Effects

Health ConditionRelationReference
Infective endocarditisCausesPMC12967059
Periodontal diseaseCausesPMC6060398
Aggressive forms of periodontitisCausesPMC7878225
Aggressive periodontitisCausesPMC7878225
AgpCausesPMC4646740
Periodontal diseasesCausesPMC3664057

Displaying health effects 1 – 6 of 6 in total