Vibrio cholerae

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Vibrionales

Family

Vibrionaceae

Genus

Vibrio

Description

Vibrio cholerae is a Gram-negative, rod-shaped bacterium characterized by its single-cell arrangement and the presence of a true flagellum, which aids in motility. This facultative anaerobe displays a heterotrophic nutritional mode, enabling it to utilize organic compounds for energy. Optimal growth occurs at a temperature of around 20°C, classifying it as mesophilic, and it thrives in various habitats, indicating its adaptability to different environmental conditions. Vibrio cholerae has a unique cellular structure, consisting of two membranes and a singular replicon, with its genomic information cataloged under accession RHPA00000000.1. As a free-living microbe, it engages in biotic relationships that may involve interactions with other microorganisms or environmental factors. Importantly, Vibrio cholerae is recognized for its pathogenicity in humans, contributing to significant health challenges, particularly in aquatic environments. The organism's ability to survive and proliferate in diverse habitats underscores its ecological versatility and the potential for environmental factors to influence its pathogenic behavior. This adaptability may play a crucial role in the dynamics of cholera outbreaks, particularly in regions with fluctuating water quality and temperature.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderVibrionales
FamilyVibrionaceae
GenusVibrio
SpeciesVibrio cholerae
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Vibrio cholerae
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature20
Temperature rangeMesophilic
HabitatMultiple
Biotic relationshipFree living
Host(s)Homo sapiens, Mollusca, Mammalia
Cell arrangementSingles
SporulationNonsporulating
Energy sourceHeterotroph
PathogenicityHuman

Genome Summary

Vibrio cholerae strain O75TS

Gene Summary

Adenine Count

1078901 bp

Thymine Count

1085544 bp

Guanine Count

974937 bp

Cytosine Count

970092 bp

Genome Length

4109474 bp

Protein-coding Genes

3598 genes

Non-Coding Genes

195 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
16s rrna (guanine(966)-n(2))-methyltransferase rsmdEEJ33_00875Not AvailablePositive197373 - 19797222820.6
duf1145 domain-containing proteinEEJ33_00880Not AvailablePositive197969 - 19823510196.3
lysoplasmalogenaseEEJ33_00885Not AvailableNegative198287 - 19891623353.4
hypothetical proteinEEJ33_00890Not AvailableNegative199033 - 19933512042.2
hypothetical proteinEEJ33_00895Not AvailablePositive199651 - 1997312856.84
duf4145 domain-containing proteinEEJ33_00900Not AvailableNegative199793 - 20016114790.0
duf2500 domain-containing proteinEEJ33_00905Not AvailablePositive200365 - 20069412747.5
dna starvation/stationary phase protection proteinEEJ33_00910Not AvailablePositive200865 - 20133517888.3
eal domain-containing proteinEEJ33_00915Not AvailableNegative201515 - 20274147638.6
homoserine/homoserine lactone efflux proteinEEJ33_00920Not AvailableNegative202761 - 20337822070.6

Displaying genes 271 – 280 of 3793 in total

Metabolites

190 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000387(6R)-5,10-methylene-5,6,7,8-tetrahydrofolateC20H21N7O6Chemical structure of (6R)-5,10-methylene-5,6,7,8-tetrahydrofolateNot available
Average455.432Da
Monoisotopic455.1564286Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000950L-xyluloseC5H10O5Chemical structure of L-xylulose527-50-4
Average150.1299Da
Monoisotopic150.05282343Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00013353-oxo-3-phenylpropanoateC9H7O3Chemical structure of 3-oxo-3-phenylpropanoateNot available
Average163.153Da
Monoisotopic163.0400677Da
BASm0001785(2R,3R)-tartrateC4H6O6Chemical structure of (2R,3R)-tartrate87-69-4
Average150.0868Da
Monoisotopic150.0164379Da
BASm0001865diphosphateHO7P2Chemical structure of diphosphateNot available
Average174.95Da
Monoisotopic174.9213971Da
BASm0002198beta-D-ribofuranoseC5H10O5Chemical structure of beta-D-ribofuranose50-69-1
Average150.1299Da
Monoisotopic150.05282343Da

Displaying 1–10 of 190 metabolites

Health Effects

Health ConditionRelationReference
CholeraCausesPMC10103850
Ear infectionsCausesPMC10103850
Wound infectionsCausesPMC10103850
SepticaemiaCausesPMC10103850
Gastrointestinal infectionsCausesPMC10103850
Necrotizing fasciitisCausesPMC10103850
VibriosisCausesPMC10472736
PneumoniaCausesPMC12801787
GastroenteritisCausesPMC12801787
SinusitisCausesPMC12801787

Displaying health effects 1 – 10 of 38 in total