Shigella dysenteriae

Gram-negativeRodNon-motileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Shigella

Description

Shigella dysenteriae is a Gram-negative, non-motile rod-shaped bacterium characterized by its facultative anaerobic metabolism and mesophilic growth preferences, with an optimal temperature of 37°C. This organism typically exists in pairs or as single cells and features two cellular membranes. It is a chemoorganotroph, deriving energy from organic compounds, and is primarily associated with host environments. S. dysenteriae is distinguished by its unique genomic structure, possessing three replicons. The genome is accessible through several accessions, including UAUQ00000000.1, UYIS00000000.1, and RTCP00000000.1. Its biotic relationship is defined as free-living, indicating its ability to thrive in association with hosts while possibly exhibiting some degree of independence from a specific host environment. This bacterium's ecological role is significant, as it is adapted to a host-associated habitat, suggesting that it may play a part in the microbial communities found within the gastrointestinal tracts of various hosts. The presence of flagella, despite its non-motility, underscores adaptation strategies that may facilitate its survival and interaction within the host environment.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusShigella
SpeciesShigella dysenteriae
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityNo
Flagellar presenceYes
Number of membranes2
Image of Shigella dysenteriae
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Metazoa, Primates
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceChemoorganotroph
PathogenicityNot Available

Genome Summary

Shigella dysenteriae strain 447529

Gene Summary

Adenine Count

1232144 bp

Thymine Count

1216307 bp

Guanine Count

1250889 bp

Cytosine Count

1272262 bp

Genome Length

4982938 bp

Protein-coding Genes

4744 genes

Non-Coding Genes

267 genes

# of Chromosomes/Plasmids

3

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
bifunctional folylpolyglutamate synthase/ dihydrofolate synthaseNCTC4837_02342Not AvailablePositive2015767 - 201703545381.1
putative lipoproteinNCTC4837_02343Not AvailablePositive2017025 - 201768722921.7
colicin v production proteinNCTC4837_02344Not AvailablePositive2018128 - 201861617991.0
amidophosphoribosyltransferaseNCTC4837_02345Not AvailablePositive2018653 - 202017056502.4
3-octaprenyl-4-hydroxybenzoate carboxy-lyaseNCTC4837_02346Not AvailablePositive2020265 - 202083420696.3
lysine-arginine-ornithine-binding periplasmic proteinNCTC4837_02347Not AvailablePositive2021099 - 202188128001.2
histidine abc transporter substrate-binding protein hisjNCTC4837_02348Not AvailablePositive2022102 - 202288428510.9
histidine abc transporter permease hisqNCTC4837_02349Not AvailablePositive2022974 - 202366024634.8
histidine abc transporter permease hismNCTC4837_02350Not AvailablePositive2023657 - 202437326871.3
histidine/lysine/arginine/ornithine transporter subunitNCTC4837_02351Not AvailablePositive2024381 - 202515428612.7

Displaying genes 7601 – 7610 of 10600 in total

Pathways

0 pathways

No pathways found

No metabolic pathways have been associated with this bacterium yet.

Metabolites

0 records
Metabolite IDMetabolite nameStructureCAS number
No metabolites foundTry different search terms or mass values.

Displaying 0 metabolites

Health Effects

Health ConditionRelationReference
ShigellosisCausesPMC5177732
HusCausesPMC7320338
ShigellosisCausesPMC8742002
Bacillary dysenteryCausesPMC8742002
Bacillary dysenteryCausesPMC11098424
Bacillary dysenteryCausesPMC11143797
ShigellosisCausesPMC11143797
Epidemic shigella dysenteryCausesPMC4445032

Displaying health effects 1 – 8 of 8 in total