Klebsiella pneumoniae str. AHEPA1046

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella pneumoniae strain AHEPA1046 is a Gram-negative, rod-shaped bacterium that typically exhibits cell arrangements in pairs, chains, or as single cells. This strain is classified as a nonsporulating organism and is optimized for growth at an environmental temperature of 37.0°C, which corresponds to the human body temperature, suggesting a close association with host environments. As a chemoheterotroph, K. pneumoniae AHEPA1046 derives its energy from organic compounds, enabling it to thrive in host-associated habitats. Additionally, this strain is a facultative anaerobe, indicating its ability to grow in both aerobic and anaerobic conditions. This metabolic versatility allows K. pneumoniae AHEPA1046 to adapt to various environments within the host, potentially contributing to its survival in diverse niches, such as in the gastrointestinal tract or other tissues. The combination of its morphological characteristics, energy acquisition strategy, and oxygen requirements underscores its ecological role as a versatile inhabitant of host-associated environments, where it may interact with the host microbiota and contribute to the overall microbial community dynamics.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella pneumoniae
StrainAHEPA1046

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella pneumoniae str. AHEPA1046
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNonsporulating
Energy sourceChemoheterotroph
PathogenicityHuman

Genome Summary

Klebsiella pneumoniae str. AHEPA1046


Gene Summary

Adenine Count

1301324 bp

Thymine Count

1295954 bp

Guanine Count

1692185 bp

Cytosine Count

1693500 bp

Genome Length

5983257 bp

Protein-coding Genes

5726 genes

Non-Coding Genes

290 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
murein hydrolase activator nlpdFH501_07045Not AvailableNegative1326025 - 132716139361.1
protein-l-isoaspartate(d-aspartate) o-methyltransferaseFH501_07050Not AvailableNegative1327287 - 132791323422.4
5'/3'-nucleotidase sureFH501_07055Not AvailableNegative1327907 - 132866827378.6
2-c-methyl-d-erythritol 2,4-cyclodiphosphate synthaseFH501_07065Not AvailableNegative1329694 - 133017316983.6
2-c-methyl-d-erythritol 4-phosphate cytidylyltransferaseFH501_07070Not AvailableNegative1330173 - 133088325717.9
cell division protein ftsbFH501_07075Not AvailableNegative1330903 - 133122011952.1
duf3561 family proteinFH501_07080Not AvailableNegative1331361 - 133168711788.8
adenylyl-sulfate kinaseFH501_07085Not AvailableNegative1331738 - 133234322505.7
sulfate adenylyltransferase subunit cysnFH501_07090Not AvailableNegative1332343 - 133377052508.5
sulfate adenylyltransferase subunit cysdFH501_07095Not AvailableNegative1333780 - 133468835216.3

Displaying genes 1581 – 1590 of 6016 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total