Klebsiella variicola

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Klebsiella

Description

Klebsiella variicola is a Gram-negative, rod-shaped bacterium characterized by its motility and true flagella. This microbe typically exhibits a cellular arrangement in chains, pairs, or as singles, and possesses a unique structure with two cellular membranes. As a facultative anaerobe, K. variicola can thrive in both aerobic and anaerobic conditions, with an optimal growth temperature of 37°C, classifying it as mesophilic. K. variicola is primarily associated with hosts, indicating its habitat is often within living organisms, where it engages in symbiotic relationships. While K. variicola is known to be pathogenic in humans, the specific mechanisms and impacts of its pathogenicity require further exploration. The bacterium has a complex genomic architecture, comprising six replicons, which may contribute to its adaptability in various environments. The genome of K. variicola has been documented in multiple accessions, highlighting its genetic diversity and potential for further study. Understanding the ecological role and interactions of K. variicola within its host could provide insights into its function as a symbiont and its implications for human health. This duality of being both a symbiont and a pathogen emphasizes the importance of context in microbial interactions and the need for careful study of its effects in different environments.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusKlebsiella
SpeciesKlebsiella variicola
StrainNo strain

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Klebsiella variicola
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipSymbiotic
Host(s)Homo sapiens, Gallus gallus, Metazoa
Cell arrangementChains - Pairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Klebsiella variicola strain A5 NODE_3718_length_209_cov_5.78049,

Gene Summary

Adenine Count

1188863 bp

Thymine Count

1187261 bp

Guanine Count

1530612 bp

Cytosine Count

1530592 bp

Genome Length

5438074 bp

Protein-coding Genes

7660 genes

Non-Coding Genes

82 genes

# of Chromosomes/Plasmids

6

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
gntr family transcriptional regulatorCWM98_05945Not AvailableNegative1013125 - 101453752969.8
duf1127 domain-containing proteinCWM98_05950Not AvailablePositive1014715 - 10148796743.24
marr family transcriptional regulatorCWM98_05955Not AvailablePositive1015045 - 101550917494.3
hlyd family secretion proteinCWM98_05960Not AvailablePositive1015516 - 101640632931.0
serine-type d-ala-d-ala carboxypeptidaseCWM98_05965Not AvailablePositive1016446 - 101787951440.8
gtpase obgeCWM98_05970Not AvailableNegative1017931 - 101910943672.8
eama family transporterCWM98_05975Not AvailableNegative1019125 - 102003833156.9
duf4400 domain-containing proteinCWM98_05980Not AvailableNegative1020095 - 102076926162.6
hypothetical proteinCWM98_05985Not AvailableNegative1020782 - 102187942179.4
conjugal transfer protein tradCWM98_05990Not AvailableNegative1021882 - 102366765814.8

Displaying genes 1131 – 1140 of 26140 in total

Metabolites

1246 records
Metabolite IDMetabolite nameStructureCAS number
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm0000274aldehydo-D-galacturonateC6H9O7Chemical structure of aldehydo-D-galacturonateNot available
Average193.132Da
Monoisotopic193.0353762Da
BASm00004283-oxoadipateC6H6O5Chemical structure of 3-oxoadipateNot available
Average158.11Da
Monoisotopic158.022620453Da
BASm0000553biphenyl-2,3-diolC12H10O2Chemical structure of biphenyl-2,3-diolNot available
Average186.2066Da
Monoisotopic186.0680796Da
BASm0000592(S)-1-phenylethanolC8H10OChemical structure of (S)-1-phenylethanolNot available
Average122.1644Da
Monoisotopic122.0731649Da
BASm0000989GlycerolC3H8O3Chemical structure of Glycerol56-81-5
Average92.0938Da
Monoisotopic92.04734412Da
BASm0001003phthalateC8H4O4Chemical structure of phthalateNot available
Average164.117Da
Monoisotopic164.0120558Da
BASm0001225dodecanoateC12H23O2Chemical structure of dodecanoateNot available
Average199.3098Da
Monoisotopic199.169805Da
BASm00012442-succinylbenzoateC11H8O5Chemical structure of 2-succinylbenzoate27415-09-04
Average220.181Da
Monoisotopic220.038270517Da

Displaying 1–10 of 1246 metabolites

Health Effects

Health ConditionRelationReference
Mink pneumoniaCausesPMC11316373
EnteritisCausesPMC11316373
Urinary tract infectionCausesPMC11316373
CystitisCausesPMC11316373
PneumoniaCausesPMC11316373
MeningitisCausesPMC11316373
Liver abscessCausesPMC11316373
Endogenous endophthalmitisCausesPMC11316373
SepsisCausesPMC11316373
PneumoniaCausesPMC12198309

Displaying health effects 1 – 10 of 53 in total