Escherichia coli str. SP-16 Combo

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain SP-16 Combo is a Gram-negative, rod-shaped bacterium that typically exists in pairs or as individual cells. This strain is adapted to a host-associated habitat, indicating a potential association with specific biological environments, such as the gastrointestinal tract of animals or humans. E. coli SP-16 Combo demonstrates facultative anaerobic metabolism, allowing it to thrive in both oxygen-rich and low-oxygen conditions, which is a common characteristic of many E. coli strains. The optimal growth temperature for E. coli SP-16 Combo is 37.0 °C, which is consistent with the physiological temperature of warm-blooded hosts, further emphasizing its adaptation to a host-associated lifestyle. This temperature preference suggests that E. coli SP-16 Combo may play a role in the microbial community dynamics within its host environment, potentially influencing nutrient cycling and microbial interactions. Understanding the traits of E. coli SP-16 Combo can offer insights into its ecological roles, particularly in relation to its interactions with the host's immune system and other microbial species. Its facultative anaerobic nature may provide it with a competitive advantage in fluctuating oxygen conditions within the host, contributing to its persistence and adaptability in complex microbial ecosystems.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainSP-16 Combo

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli str. SP-16 Combo
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain SP-16 Combo

Gene Summary

Adenine Count

1503507 bp

Thymine Count

1502171 bp

Guanine Count

1534771 bp

Cytosine Count

1540882 bp

Genome Length

6081331 bp

Protein-coding Genes

7256 genes

Non-Coding Genes

466 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
multidrug resistance transporterC1I57_36265Not AvailableNegative5832859 - 583325014475.6
succinate--coa ligase subunit alphaC1I57_36270Not AvailableNegative5833251 - 583364213416.5
succinate--coa ligase subunit alphaC1I57_36275Not AvailableNegative5833643 - 583403413416.5
imidazole glycerol phosphate synthase subunit hisfC1I57_36280Not AvailablePositive5834035 - 583440013549.1
hypothetical proteinC1I57_36285Not AvailablePositive5834427 - 583481814324.7
hypothetical proteinC1I57_36290Not AvailablePositive5834819 - 583521014314.7
oxidoreductaseC1I57_36295Not AvailableNegative5835211 - 583560114313.0
diguanylate cyclaseC1I57_36300Not AvailableNegative5835602 - 583599214787.0
sulfurtransferase tusaC1I57_36305Not AvailablePositive5836029 - 58362749167.15
pyrimidine utilization protein bC1I57_36310Not AvailableNegative5836775 - 583716414524.3

Displaying genes 6961 – 6970 of 7722 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total