Escherichia coli str. NUBRI-E

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli strain NUBRI-E is a Gram-negative, rod-shaped bacterium that typically exists in pairs or as single cells. This strain is classified as a facultative anaerobe, indicating its ability to thrive in both aerobic and anaerobic environments. E. coli NUBRI-E has an optimal growth temperature of 37.0 °C, which aligns with the physiological temperature of many mammalian hosts, suggesting a potential adaptation for survival within host-associated habitats. The ability of E. coli NUBRI-E to inhabit host-associated environments reflects its versatile metabolic capabilities, allowing it to utilize various substrates for energy production. This adaptability may enhance its survival in diverse ecological niches, particularly within the gastrointestinal tracts of warm-blooded animals. The facultative anaerobic nature of this strain further implies that it can efficiently switch between aerobic respiration and fermentation, providing a competitive advantage in fluctuating oxygen conditions commonly found in host environments. Understanding the traits of E. coli NUBRI-E can offer insights into its role in microbial communities associated with hosts, where it may contribute to essential processes such as nutrient cycling and maintaining gut homeostasis. The strain's metabolic flexibility and optimal growth temperature suggest a sophisticated adaptation to host-associated life, highlighting the intricate relationships between microbial inhabitants and their hosts.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
StrainNUBRI-E

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli str. NUBRI-E
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain NUBRI-E 156, whole genome shotgun

Gene Summary

Adenine Count

1290282 bp

Thymine Count

1291497 bp

Guanine Count

1342139 bp

Cytosine Count

1315095 bp

Genome Length

5239013 bp

Protein-coding Genes

4761 genes

Non-Coding Genes

392 genes

# of Chromosomes/Plasmids

1

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
Replication proteinE1729_09340Not AvailablePositive1901411 - 1904233106871.0
RecombinaseE1729_09345Not AvailablePositive1904310 - 190526935024.9
Plasmid partitioning/stability family proteinE1729_09350Not AvailablePositive1905274 - 190558811939.2
hypothetical proteinE1729_09355Not AvailableNegative1905672 - 190651432951.1
duf4760 domain-containing proteinE1729_09360Not AvailableNegative1906554 - 190705119385.5
hypothetical proteinE1729_09365Not AvailablePositive1907775 - 190829919778.4
Pbsx family portal proteinE1729_09370Not AvailableNegative1908314 - 190936039275.1
Helix-turn-helix domain-containing proteinE1729_09375Not AvailableNegative1909360 - 191111166831.5
Capsid scaffolding proteinE1729_09380Not AvailablePositive1911266 - 191210230721.1
Major capsid protein, p2 familyE1729_09385Not AvailablePositive1912126 - 191317839306.5

Displaying genes 151 – 160 of 5153 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total