Escherichia coli str. E4223

Escherichia coli str. E4223 is a Gram-negative, rod-shaped bacterium that typically arranges itself in pairs or as single cells. This strain thrives optimally at a temperature of 37.0°C, which coincides with the average body temperature of many warm-blooded hosts, indicating a potential adaptation to a host-associated habitat. E. coli str. E4223 is classified as a facultative anaerobe, allowing it to grow in both aerobic and anaerobic conditions, which further supports its versatility in various host environments. The strain's association with host organisms suggests that it may play a role in the microbiota of the intestinal tract, contributing to essential metabolic functions or interactions with the host immune system. This adaptability to different oxygen levels may facilitate its survival in diverse microenvironments within the host, including those that experience fluctuations in oxygen availability. Understanding the traits of E. coli str. E4223 can provide insights into its ecological role, particularly in how it might influence host health or contribute to the microbial community dynamics within the gastrointestinal tract. As a member of the E. coli species, this strain may also help elucidate the complexities of host-microbe interactions, particularly in terms of nutrient utilization and microbial competition.