Escherichia coli str. 28RC1

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli str. 28RC1 is a Gram-negative, rod-shaped bacterium that typically exists in pairs or as single cells. This strain thrives optimally at a temperature of 37.0 °C, which aligns with the normal body temperature of many host organisms, suggesting a potential adaptation to life within a host-associated habitat. As a facultative anaerobe, E. coli str. 28RC1 can survive in both aerobic and anaerobic environments, allowing it to exploit a diverse range of ecological niches within the host. The structural characteristics of this strain, such as its rod shape and specific cell arrangement, may contribute to its interactions within the host environment. The ability to form pairs could facilitate cellular communication or biofilm formation under certain conditions, enhancing its survival and functionality within the host. This strain exemplifies the metabolic versatility and adaptability often seen in E. coli, emphasizing its potential role in various host-associated ecosystems. Understanding these traits may provide insights into the ecological dynamics and functional roles that E. coli str. 28RC1 plays in its specific habitat, which could be crucial for deciphering its interactions with both the host and other microbial communities.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strain28RC1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli str. 28RC1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 28RC1 chromosome, complete genome.

Gene Summary

Adenine Count

1377407 bp

Thymine Count

1371115 bp

Guanine Count

1411082 bp

Cytosine Count

1402094 bp

Genome Length

5561698 bp

Protein-coding Genes

4589 genes

Non-Coding Genes

1027 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
ribosome-associated protein ybcjARC77_RS22345Not AvailableNegative4416694 - 44169067389.95
bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase foldARC77_RS22350Not AvailableNegative4416908 - 441777430957.5
type 1 fimbrial major subunit fimaARC77_RS22355Not AvailablePositive4418254 - 441879618475.5
type 1 fimbria chaperone fimcARC77_RS22360Not AvailablePositive4419016 - 441970825487.2
fimbrial biogenesis usher proteinARC77_RS22365Not AvailablePositive4419739 - 442234896104.7
type 1 fimbria d-mannose specific adhesin fimhARC77_RS22370Not AvailablePositive4422361 - 442336836614.0
fimbria assembly proteinARC77_RS22375Not AvailablePositive4423379 - 442389418213.6
fimbria biosynthesis transcriptional regulator fimzARC77_RS22380Not AvailableNegative4423897 - 442452923664.9
Trna-argNot AvailableNot AvailablePositive4424772 - 4424848Not Available
dna-binding transcriptional regulator envyARC77_RS22390Not AvailableNegative4424894 - 442565528992.5

Displaying genes 4791 – 4800 of 5708 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total