Escherichia coli str. 28RC1

Gram-negativeRodMotileFacultative anaerobe

Kingdom

Pseudomonadati

Phylum

Pseudomonadota

Class

Gammaproteobacteria

Order

Enterobacterales

Family

Enterobacteriaceae

Genus

Escherichia

Description

Escherichia coli str. 28RC1 is a Gram-negative, rod-shaped bacterium that typically exists in pairs or as single cells. This strain thrives optimally at a temperature of 37.0 °C, which aligns with the normal body temperature of many host organisms, suggesting a potential adaptation to life within a host-associated habitat. As a facultative anaerobe, E. coli str. 28RC1 can survive in both aerobic and anaerobic environments, allowing it to exploit a diverse range of ecological niches within the host. The structural characteristics of this strain, such as its rod shape and specific cell arrangement, may contribute to its interactions within the host environment. The ability to form pairs could facilitate cellular communication or biofilm formation under certain conditions, enhancing its survival and functionality within the host. This strain exemplifies the metabolic versatility and adaptability often seen in E. coli, emphasizing its potential role in various host-associated ecosystems. Understanding these traits may provide insights into the ecological dynamics and functional roles that E. coli str. 28RC1 plays in its specific habitat, which could be crucial for deciphering its interactions with both the host and other microbial communities.

Taxonomy

KingdomPseudomonadati
PhylumPseudomonadota
ClassGammaproteobacteria
OrderEnterobacterales
FamilyEnterobacteriaceae
GenusEscherichia
SpeciesEscherichia coli
Strain28RC1

Profile

Physiology
Gram staining propertiesNegative
ShapeRod
MobilityYes
Flagellar presenceYes
Number of membranes2
Image of Escherichia coli str. 28RC1
Image source: Wikipedia/Wikimedia
Ecology, Host, and Life Cycle
Oxygen requirementsFacultative anaerobe
Optimal temperature37
Temperature rangeMesophilic
HabitatHostAssociated
Biotic relationshipFree living
Host(s)Homo sapiens, Gallus gallus, Bos taurus
Cell arrangementPairs - Singles
SporulationNot Available
Energy sourceNot Available
PathogenicityHuman

Genome Summary

Escherichia coli strain 28RC1 chromosome, complete genome.

Gene Summary

Adenine Count

1377407 bp

Thymine Count

1371115 bp

Guanine Count

1411082 bp

Cytosine Count

1402094 bp

Genome Length

5561698 bp

Protein-coding Genes

4589 genes

Non-Coding Genes

1027 genes

# of Chromosomes/Plasmids

2

Genes

NameLocus TagUniProt IDStrand OrientationGene Start/EndProtein Molecular Weight
class i fumarate hydrataseARC77_RS17865Not AvailableNegative3461923 - 346356960143.8
anaerobic c4-dicarboxylate transporter dcubARC77_RS17870Not AvailableNegative3463647 - 346498747938.2
two-component system response regulator dcurARC77_RS17880Not AvailableNegative3465558 - 346627727489.9
sensor histidine kinaseARC77_RS17885Not AvailableNegative3466274 - 346790560554.4
4fe-4s mono-cluster protein yjdiARC77_RS17890Not AvailablePositive3468086 - 34683168550.35
gnat family n-acetyltransferaseARC77_RS17895Not AvailablePositive3468328 - 346860010469.6
type v toxin-antitoxin system endoribonuclease antitoxin ghosARC77_RS17905Not AvailablePositive3468827 - 346912311468.6
type v toxin-antitoxin system toxin ghotARC77_RS17910Not AvailablePositive3469151 - 34693246555.44
lysine--trna ligaseARC77_RS17915Not AvailableNegative3469443 - 347096057829.9
dipeptide/tripeptide permease dtpcARC77_RS17920Not AvailableNegative3471197 - 347265453010.6

Displaying genes 3961 – 3970 of 5708 in total

Metabolites

4785 records
Metabolite IDMetabolite nameStructureCAS number
BASm0000173(R)-3-Hydroxybutyric acidC4H8O3Chemical structure of (R)-3-Hydroxybutyric acid625-72-3
Average104.0473Da
Monoisotopic104.047344122Da
BASm0000217alpha-ribazoleC14H18N2O4Chemical structure of alpha-ribazoleNot available
Average278.3037Da
Monoisotopic278.126657074Da
BASm0000237(R)-4'-phosphopantothenateC9H18NO8PChemical structure of (R)-4'-phosphopantothenateNot available
Average299.2149Da
Monoisotopic299.0770031Da
BASm0000238(R)-3-phenyllactateC9H9O3Chemical structure of (R)-3-phenyllactateNot available
Average165.169Da
Monoisotopic165.05571773Da
BASm00002482,3-dihydroxy-3-methylbutanoateC5H10O4Chemical structure of 2,3-dihydroxy-3-methylbutanoate1756-18-9
Average134.1305Da
Monoisotopic134.0579088Da
BASm00002502,5-didehydro-D-gluconateC6H7O7Chemical structure of 2,5-didehydro-D-gluconate53736-12-2
Average191.1156Da
Monoisotopic191.019177578Da
BASm00002512-dehydropantoateC6H9O4Chemical structure of 2-dehydropantoateNot available
Average145.1333Da
Monoisotopic145.050083776Da
BASm00002532-oxopent-4-enoateC5H5O3Chemical structure of 2-oxopent-4-enoateNot available
Average113.093Da
Monoisotopic113.024417601Da
BASm00002593alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,12alpha-dihydroxy-7-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da
BASm00002603alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateC24H37O5Chemical structure of 3alpha,7alpha-dihydroxy-12-oxo-5beta-cholanateNot available
Average405.556Da
Monoisotopic405.264647871Da

Displaying 1–10 of 4785 metabolites

Health Effects

Health ConditionRelationReference
Gi diseaseCausesPMC11149725
UtisCausesPMC11434687
Colorectal cancerCausesPMC12198655
Pyogenic liver abscessesCausesPMC12392612
UtiCausesPMC13014981
ColibacillosisCausesPMC13255289
Enteric infectionsCausesPMC13255289
Foodborne infectionsCausesPMC13255289
Clinical mastitisCausesPMC13293316
DiarrheaCausesPMC3035056

Displaying health effects 1 – 10 of 103 in total